Results 51 to 60 of about 8,743,254 (323)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Verbatim: Archiving Qualitative Data and Secondary Analysis in a French Company

Forum: Qualitative Social Research, 2000
Archiving qualitative data analysis and secondary analysis, first developed in the USA and in the Northern European countries, is not a current practice in France. To our knowledge, we are the first to have developed it in a French context.
Dominique Le Roux, Jean Vidal
doaj  

The ethics of using generative AI for qualitative data analysis

Information Systems Journal
GAI
Robert M. Davison, Hameed Chughtai, Petter Nielsen, Marco Marabelli, F. Iannacci, Marjolein van Offenbeek, Monideepa Tarafdar, Manuel Trenz, A. Techatassanasoontorn, A. Díaz-Andrade, Niki Panteli   +10 more
semanticscholar   +1 more source

Complex Qualitative Data Analysis: Lessons Learned From the Experiences With the Qualitative Analysis Guide of Leuven

Qualitative Health Research, 2020
In this article, the authors discuss critical factors to be considered when analyzing complex qualitative data. The experiences with the use of the Qualitative Analysis Guide of Leuven (QUAGOL) to analyze qualitative data were used as starting point to ...
B. Dierckx de Casterlé, K. De Vliegher, C. Gastmans, Evelyne Mertens   +3 more
semanticscholar   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Identifying the Impact Factors on the Land Market in Nepal from Land Use Regulation

Urban Science
Measuring the impact of land use regulation on the land market involves identifying and classifying relevant impact factors related to the land market.
Nab Raj Subedi, Kevin McDougall, Dev Raj Paudyal   +2 more
doaj   +1 more source

Reflexive Content Analysis: An Approach to Qualitative Data Analysis, Reduction, and Description

Content analysis, initially a quantitative technique for identifying patterns in qualitative data, has evolved into a widely used qualitative method.
Mitchell Nicmanis
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source