Results 51 to 60 of about 40,671,276 (290)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Identifying the Impact Factors on the Land Market in Nepal from Land Use Regulation
Urban ScienceMeasuring the impact of land use regulation on the land market involves identifying and classifying relevant impact factors related to the land market.
Nab Raj Subedi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Verbatim: Archiving Qualitative Data and Secondary Analysis in a French Company
Forum: Qualitative Social Research, 2000 Archiving qualitative data analysis and secondary analysis, first developed in the USA and in the Northern European countries, is not a current practice in France. To our knowledge, we are the first to have developed it in a French context.
Dominique Le Roux, Jean Vidal
doaj
, 2019 Project Summary The design of the study is qualitative, it includes data from twenty in-depth interviews with the mothers of Severe acute malnutrition (SAM) and Moderate acute malnutrition (MAM) children from seven different villages to explore the ...
Paspuleti, Shirisha
core +1 more source
Data for: The non-democratic roots of mass education: Evidence from 200 years
, 2020 This is an Annotation for Transparent Inquiry (ATI) data project. The annotated article can be viewed on the publisher's website. Project Summary This project assesses the impact of democratization on primary school enrollment rates using quantitative ...
Paglayan, Agustina
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Energy democracy in northeastern North America
, 2017 The data project has been initiated for research on energy democracy initiatives (EDI) and their transition narratives, and more broadly on social-ecological-technical systems related to renewable energy transition in the region of northeastern North ...
Burke, Matthew
core +1 more source
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source