Results 61 to 70 of about 4,403,004 (334)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Perceptions of safety during everyday travel shaping older adults’ mobility in Bengaluru, India

open access: yesBMC Public Health
Background In the context of socially sustainable urban development, comfortable, safe, and accessible public transport is crucial to motivating people to travel more sustainably. Using the framework given by Masoumi and Fastenmeier (2016) to examine the
Divya Sussana Patil   +4 more
doaj   +1 more source

A researcher's dilemma- philosphical and methodological pluralism [PDF]

open access: yes, 2004
In many research textbooks the distinction between qualitative and quantitative research is inadvertently linked with philosophical perspectives. This in essence creates a mutually exclusive relationship between method and philosophy.
Knox, KT
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Reflection of Triangulation, Case Study of Innovation Behaviors in the UAE Travel Agencies Organizations [PDF]

open access: yes, 2019
This case study validates the role of innovation behaviour in business organizations in the United Arab Emirates. Travel agencies were studied due to fast changing nature of business and environment assuming a high risk of uncertainty and dynamics of ...
Sandybayev, A. (Almaz)   +1 more
core  

Physics of String Flux Compactifications [PDF]

open access: yes, 2007
We provide a qualitative review of flux compactifications of string theory, focusing on broad physical implications and statistical methods of analysis.Comment: 39 pages, Latex ar2e ...
Denef, Frederik   +2 more
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Qualitative software engineering research -- reflections and guidelines

open access: yes, 2020
Researchers are increasingly recognizing the importance of human aspects in software development and since qualitative methods are used to, in-depth, explore human behavior, we believe that studies using such techniques will become more common ...
Feldt, Robert   +5 more
core  

A qualitative meta-synthesis: public health nurses role in the identification and management of perinatal mental health problems [PDF]

open access: yes, 2016
Aim: To report findings of a systematic review and meta-synthesis of qualitative studies exploring public health nurses’ perceptions and experiences of identifying and managing women with perinatal mental health (PMH) problems.
Doody, Owen   +3 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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