Results 101 to 110 of about 20,113,391 (246)

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Medical costs and quality-adjusted life years associated with smoking: a systematic review

open access: yesBMC Public Health, 2016
Background Estimated medical costs (“T”) and QALYs (“Q”) associated with smoking are frequently used in cost-utility analyses of tobacco control interventions.
Shari P. Feirman   +6 more
doaj   +1 more source

What can local authorities do to improve the social care-related quality of life of older adults living at home? Evidence from the Adult Social Care Survey [PDF]

open access: yes, 2014
Local authorities spend considerable resources on social care at home for older adults. Given the expected growth in the population of older adults and budget cuts on local government, it is important to find efficient ways of maintaining and improving ...
van der Horst, H.E.   +16 more
core   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Cost-utility tele-stroke in adults with acute ischemic stroke. A systematic review

open access: yesPublic Health in Practice
Introduction: Tele-Stroke has been proposed as a solution to increase access to thrombolytic therapy in acute ischemic stroke. Objective: Synthesise the evidence of the cost-effectiveness of Tele-Stroke.
Luis Alberto López-Romero   +3 more
doaj   +1 more source

Effectiveness of hip or knee replacement surgery in terms of quality-adjusted life years and costs

open access: yesActa Orthopaedica, 2007
Background Concurrent head-to-head comparisons of healthcare interventions regarding cost-utility are rare. The concept of favorable cost-effectiveness of total hip or knee arthroplasty is thus inadequately verified.
P. Räsänen   +6 more
semanticscholar   +1 more source

Quality of Life Lost Due to Non-Fatal Road Crashes [PDF]

open access: yes
The objective of this paper is to evaluate the effect of a nonfatal road crash on the health-related quality of life of injured people. A new approach is suggested, based on the cardinalization of categorical Self-Assessed Health valuations.
Cubí-Mollá Patricia, Herrero Carmen
core  

Smoking and health-related quality of life in English general population: Implications for economic evaluations [PDF]

open access: yes, 2012
Copyright @ 2012 Vogl et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution ...
Reiner Leidl   +20 more
core   +2 more sources

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Trial‐based economic evaluation of mindfulness‐based cognitive therapy compared to treatment as usual for bipolar disorder

open access: yesInternational Journal of Methods in Psychiatric Research
Objective Aim of this study was to assess the cost‐effectiveness and cost‐utility of mindfulness‐based cognitive therapy (MBCT) and treatment as usual (TAU) compared to TAU alone in adults with Bipolar disorder (BD). Methods An economic evaluation with a
Ben Wijnen   +6 more
doaj   +1 more source

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