Results 41 to 50 of about 586,644 (327)

Quality-Adjusted Life-Years without Constant Proportionality [PDF]

Value in Health, 2018
A quality-adjusted life-year is a common unit of measurement in health valuation. Under its constant proportionality assumption, the value of a quality-adjusted life span is defined as the product of preference weight and life span.To empirically identify an alternative functional relationship between life span and value by relaxing the constant ...
Peep F. M. Stalmeier, Kim Rand, Kim Rand, Benjamin M. Craig, Henry Bailey   +4 more
openaire   +3 more sources

A technique for approximating transition rates from published survival analyses

Cost Effectiveness and Resource Allocation, 2019
Background Quality-adjusted-life-years (QALYs) are used to concurrently quantify morbidity and mortality within a single parameter. For this reason, QALYs can facilitate the discussion of risks and benefits during patient counseling regarding treatment ...
Markian A. Pahuta, Joel Werier, Eugene K. Wai, Roy A. Patchell, Doug Coyle   +4 more
doaj   +1 more source

QALY losses for chronic diseases and its social distribution in the general population: results from the Belgian Health Interview Survey

BMC Public Health, 2022
Background The burden of chronic diseases is rapidly rising, both in terms of morbidity and mortality. This burden is disproportionally carried by socially disadvantaged population subgroups.
Lisa Van Wilder, Brecht Devleesschauwer, Els Clays, Johan Van der Heyden, Rana Charafeddine, Aline Scohy, Delphine De Smedt   +6 more
doaj   +1 more source

Measuring Quality-Adjusted Life-Years When Health Fluctuates [PDF]

Value in Health, 2020
Recurrent fluctuations in health states can occur as a result of long-term conditions with episodic symptoms or through side effects of cycles of treatment. Fluctuations and associated duration of symptoms can be predictable (eg, side effects of chemotherapy treatment) or unpredictable (eg, relapse in multiple sclerosis). Such recurrent fluctuations in
Sanghera, Sabina, Coast, Joanna
openaire   +4 more sources

A pharmaco-economic evaluation of deferasirox for treating patients with iron overload caused by transfusion-dependent thalassemia in Taiwan

Journal of the Formosan Medical Association, 2013
The newly available iron chelator deferasirox (Exjade, Novartis) is expected to provide better long-term clinical outcomes and improved quality of life for patients with thalassemia than its predecessor, deferoxamine (Desferal, Novartis), because of its ...
Wan-Ling Ho, Kuo-Piao Chung, Szu-Sheng Yang, Meng-Yao Lu, Shiann-Tarng Jou, Hsiu-Hao Chang, Yung-Li Yang, Dong-Tsamn Lin, Kai-Hsin Lin   +8 more
doaj   +1 more source

An exploratory study to estimate cost-effectiveness threshold value for life saving treatments in western Iran

Cost Effectiveness and Resource Allocation, 2020
Background Cost-effectiveness analysis provides a crucial means for evidence-informed decision-making on resource allocation. This study aims to elicit individuals' willingness to pay (WTP) for one additional quality-adjusted life-year (QALY) gained from
Najmeh Moradi, Abraha Woldemichael, Parisa Malekian, Delnia Moradi Rotvandi, Satar Rezaei   +4 more
doaj   +1 more source

Putting the quality into quality-adjusted life years [PDF]

Journal of Public Health, 2003
Over recent decades, a great deal of effort has been devoted towards developing instruments that can be used to elicit health state values. All of these instruments are conceptually very different from one another and all suffer from serious inherent biases.
openaire   +3 more sources

Incremental cost per quality-adjusted life year gained? The need for alternative methods to evaluate medical interventions for ultra-rare disorders.

Journal of Comparative Effectiveness Research, 2014
M. Schlander, S. Garattini, S. Holm, P. Kolominsky-Rabas, E. Nord, U. Persson, M. Postma, J. Richardson, S. Simoens, Oriol de Solà Morales, K. Tolley, M. Toumi   +11 more
semanticscholar   +2 more sources

Reference‐dependent age weighting of quality‐adjusted life years

Health Economics, 2022
ABSTRACTPeople do not only care about maximizing health gains but also about their distribution. For example, they give more weight to younger patients than older patients. This pilot study aims to investigate if age weighting is reinforced by loss aversion if young people are falling behind one's perceived ‘normal’ quality of life (QoL), while older ...
Arthur E. Attema, Werner B. F. Brouwer, Jose Luis Pinto‐Prades   +2 more
openaire   +3 more sources

THE USE OF QALY AS AN INTEGRAL MEASURE OF EFFECTIVENESS IN THE EVALUATION OF MEDICAL TECHNOLOGIES

Фармакоэкономика, 2017
This report addresses the ways of calculating QALY (Quality-adjusted life-year). OutsideRussia, a standardized methodology to calculate QALY is in use; such an approach makes it possible to apply this universal criterion of effectiveness to the ...
N. Z. Musina, V. K. Fedyaeva
doaj   +1 more source