Results 111 to 120 of about 1,647,697 (336)

Decision-analytic cost-effectiveness model to compare prostate cryotherapy to androgen deprivation therapy for treatment of radiation recurrent prostate cancer [PDF]

open access: yes, 2015
Objective: To determine the cost-effectiveness of salvage cryotherapy (SC) in men with radiation recurrent prostate cancer (RRPC). Design: Cost-utility analysis using decision analytic modelling by a Markov model.
Birrell, Fiona   +5 more
core   +2 more sources

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

Medical costs and quality-adjusted life years associated with smoking: a systematic review

open access: yesBMC Public Health, 2016
Background Estimated medical costs (“T”) and QALYs (“Q”) associated with smoking are frequently used in cost-utility analyses of tobacco control interventions.
Shari P. Feirman   +6 more
doaj   +1 more source

Clinimetrics: The quality adjusted life year

open access: yesJournal of Physiotherapy, 2023
Sheraya De Silva, Alisa M Higgins
openaire   +2 more sources

Impact of generic alendronate cost on the cost-effectiveness of osteoporosis screening and treatment [PDF]

open access: yes, 2012
Introduction: Since alendronate became available in generic form in the Unites States in 2008, its price has been decreasing. The objective of this study was to investigate the impact of alendronate cost on the cost-effectiveness of osteoporosis ...
A Oleksik   +48 more
core   +6 more sources

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Health effects of home energy efficiency interventions in England: a modelling study [PDF]

open access: yes, 2015
Objective: To assess potential public health impacts of changes to indoor air quality and temperature due to energy efficiency retrofits in English dwellings to meet 2030 carbon reduction targets. Design: Health impact modelling study.
Chalabi, Z   +7 more
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Cost-utility tele-stroke in adults with acute ischemic stroke. A systematic review

open access: yesPublic Health in Practice
Introduction: Tele-Stroke has been proposed as a solution to increase access to thrombolytic therapy in acute ischemic stroke. Objective: Synthesise the evidence of the cost-effectiveness of Tele-Stroke.
Luis Alberto López-Romero   +3 more
doaj   +1 more source

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