Results 91 to 100 of about 20,675,763 (300)

Cost-Utility Analysis of Rosuvastatin (20 mg) to Prevent Cardiovascular Diseases in Iran

Advanced Biomedical Research
Background: Cardiovascular diseases are a main cause of disease burden in developing and developed countries. This study aimed to evaluate the cost-utility of rosuvastatin 20 mg in contrast with no intervention for the prevention of cardiovascular ...
Aziz Rezapour, Abdosaleh Jafari, Hamid Talebianpour   +2 more
doaj   +1 more source

Economic evaluation of an extended nutritional intervention in older Australian hospitalized patients: a randomized controlled trial

BMC Geriatrics, 2018
Background Prevalence of malnutrition in older hospitalized patients is 30%. Malnutrition is associated with poor clinical outcomes in terms of high morbidity and mortality and is costly for hospitals.
Yogesh Sharma, Campbell Thompson, Michelle Miller, Rashmi Shahi, Paul Hakendorf, Chris Horwood, Billingsley Kaambwa   +6 more
doaj   +1 more source

Disability-adjusted life years (DALYs) based COVID-19 health impact assessment: A systematic review

, 2023
Background The emergence of COVID-19 has resulted in health, socio-economic, and political crises. The overall health impact of this disease can be measured by disability-adjusted life years (DALYs) which is the sum of the life years lost due to ...
Islam, Md Shahidul, Wark, Stuart, Gebeyehu, Daniel Teshome, East, Leah, Md Shahidul Islam, Leah East, Daniel Teshome Gebeyehu, Stuart Wark   +7 more
core   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Oral splints for patients with temporomandibular disorders or bruxism: a systematic review and economic evaluation

Health Technology Assessment, 2020
Background: Splints are a non-invasive, reversible management option for temporomandibular disorders or bruxism. The clinical effectiveness and cost-effectiveness of splints remain uncertain.
Philip Riley, Anne-Marie Glenny, Helen V Worthington, Elisabet Jacobsen, Clare Robertson, Justin Durham, Stephen Davies, Helen Petersen, Dwayne Boyers   +8 more
doaj   +1 more source

The projected changes in quality adjusted life years lost related to COPD in Canada in men (A) and women (B).

, 2012
The projected changes in quality adjusted life years lost related to COPD in Canada in men (A) and women (B).
Larry D. Lynd (115952), Mehdi Najafzadeh (128547), Mohsen Sadatsafavi (63962), J. Mark FitzGerald (115951), Bruce McManus (128550), Don Sin (128552), Carlo A. Marra (115949)   +6 more
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Medical costs and quality-adjusted life years associated with smoking: a systematic review

BMC Public Health, 2016
Background Estimated medical costs (“T”) and QALYs (“Q”) associated with smoking are frequently used in cost-utility analyses of tobacco control interventions.
Shari P. Feirman, Allison M. Glasser, Lyubov Teplitskaya, David R. Holtgrave, David B. Abrams, Raymond S. Niaura, Andrea C. Villanti   +6 more
doaj   +1 more source

Cost-utility model input parameters: Principal event probabilities, lifetime costs and quality-adjusted life years.

Cost-utility model input parameters: Principal event probabilities, lifetime costs and quality-adjusted life years.
Dyfrig Hughes (40543), Bernd Duller (3834748), Elke Naujokat (18358266), Huw Lloyd Williams (18495674), Emily Holmes (418302), Christian P. Subbe (18495677)   +5 more
core   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source