Results 91 to 100 of about 1,728,986 (343)

Decision-analytic cost-effectiveness model to compare prostate cryotherapy to androgen deprivation therapy for treatment of radiation recurrent prostate cancer [PDF]

, 2015
Objective: To determine the cost-effectiveness of salvage cryotherapy (SC) in men with radiation recurrent prostate cancer (RRPC). Design: Cost-utility analysis using decision analytic modelling by a Markov model.
Birrell, Fiona, Boyd, Kathleen A., Briggs, Andrew H., Jones, Rob J., Leung, Hing Y., Paul, Jim   +5 more
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Cost-Effectiveness of Strategies to Improve HIV Testing and Receipt of Results: Economic Analysis of a Randomized Controlled Trial [PDF]

, 2010
The CDC recommends routine voluntary HIV testing of all patients 13-64 years of age. Despite this recommendation, HIV testing rates are low even among those at identifiable risk, and many patients do not return to receive their results.
Gillian D. Sanders, Henry D. Anaya, Steven Asch, Tuyen Hoang, Joya F. Golden, Ahmed M. Bayoumi, Douglas K. Owens, BM Branson, PM Wortley, G Marks, Centers for Disease Control and Prevention, HI Hall, A Qaseem, AD Paltiel, AD Paltiel, GD Sanders, GD Sanders, DK Owens, G Tao, AB Hutchinson, HD Anaya, MC Weinstein, JR Beck, FA Sonnenberg, BA Koblin, AN Phillips, JT King Jr, PS Rosenberg, JM Karon, JM Karon, DG Fryback, J Atri, VA Cargill, VL Champion, JJ Gonzalez, J Robson, EG Stone, CA Metcalf, SB Lyss, WJ Kassler, JS Haukoos, A Silva, PG Farnham, SD Mehta, RP Walensky, JL Greenwald, PG Yeni   +46 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

The STAR trial protocol: a randomised multi-stage phase II/III study of Sunitinib comparing temporary cessation with allowing continuation, at the time of maximal radiological response, in the first-line treatment of locally advanced/metastatic Renal Cancer

BMC Cancer, 2012
Background Over recent years a number of novel therapies have shown promise in advanced renal cell carcinoma (RCC). Internationally the standard of care of first-line therapy is sunitinib™, after a clear survival benefit was demonstrated over interferon ...
Collinson Fiona J, Gregory Walter M, McCabe Chris, Howard Helen, Lowe Catherine, Potrata DrBarbara, Tubeuf Sandy, Hanlon Pat, McParland Lucy, Wah T, Selby Peter J, Hewison Jenny, Brown Julia, Brown Janet   +13 more
doaj   +1 more source

Costs, quality-adjusted life years, and value-of-information of different thresholds for the initiation of invasive ventilation in hypoxemic respiratory failure [PDF]

, 2023
Christopher J. Yarnell, Kali Barrett, Anna Heath, Margaret S. Herridge, Rob Fowler, Lillian Sung, David Naimark, George Tomlinson   +7 more
openalex   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

The concept of quality of life in oncology [PDF]

Archive of Oncology, 2004
Osoba David
doaj   +1 more source

Long-term cost-effectiveness of pharmacist-managed hypertension care in China

BMC Health Services Research
Background Hypertension is one of the main causes of cardiovascular and kidney diseases in China. However, the rate of effective blood pressure control remains low.
Jingxuan Wei, Lihong Gao, Zhuying Jing, Jia Wang, Yulu Zhu, Haomin Zhu, Xin Li   +6 more
doaj   +1 more source

The economic consequences of attention-deficit hyperactivity disorder in the Scottish prison system

BMC Psychiatry, 2018
Background Attention-deficit hyperactivity disorder (ADHD) is highly prevalent amongst prison inmates and the criminal justice system (CJS) likely bears considerable costs for offenders with ADHD.
Susan Young, Rafael A. González, Moshe Fridman, Paul Hodgkins, Keira Kim, Gisli H. Gudjonsson   +5 more
doaj   +1 more source