Results 81 to 90 of about 19,641,026 (283)

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

QALY losses for non-communicable diseases in Iranian adults: insights from a national cross-sectional study

Population Health Metrics
Background Non-communicable diseases (NCDs), constitute a major global public health challenge and represent the primary causes of mortality and morbidity worldwide. This study aims to estimate Quality-Adjusted Life Year (QALY) losses associated with six
Abdoreza Mousavi, Satar Rezaei, Ali Akbari Sari, Mohammad Amin Masoumi, Rajabali Daroudi   +4 more
doaj   +1 more source

Cost-Utility Analysis of Rosuvastatin (20 mg) to Prevent Cardiovascular Diseases in Iran

Advanced Biomedical Research
Background: Cardiovascular diseases are a main cause of disease burden in developing and developed countries. This study aimed to evaluate the cost-utility of rosuvastatin 20 mg in contrast with no intervention for the prevention of cardiovascular ...
Aziz Rezapour, Abdosaleh Jafari, Hamid Talebianpour   +2 more
doaj   +1 more source

Economic evaluation of an extended nutritional intervention in older Australian hospitalized patients: a randomized controlled trial

BMC Geriatrics, 2018
Background Prevalence of malnutrition in older hospitalized patients is 30%. Malnutrition is associated with poor clinical outcomes in terms of high morbidity and mortality and is costly for hospitals.
Yogesh Sharma, Campbell Thompson, Michelle Miller, Rashmi Shahi, Paul Hakendorf, Chris Horwood, Billingsley Kaambwa   +6 more
doaj   +1 more source

Measuring health and subjective wellbeing: vale, quality-adjusted life-years

, 2005
Measuring health and subjective wellbeing: vale, quality-adjusted life ...
Robert Cummins (13065627)
core  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Oral splints for patients with temporomandibular disorders or bruxism: a systematic review and economic evaluation

Health Technology Assessment, 2020
Background: Splints are a non-invasive, reversible management option for temporomandibular disorders or bruxism. The clinical effectiveness and cost-effectiveness of splints remain uncertain.
Philip Riley, Anne-Marie Glenny, Helen V Worthington, Elisabet Jacobsen, Clare Robertson, Justin Durham, Stephen Davies, Helen Petersen, Dwayne Boyers   +8 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Medical costs and quality-adjusted life years associated with smoking: a systematic review

BMC Public Health, 2016
Background Estimated medical costs (“T”) and QALYs (“Q”) associated with smoking are frequently used in cost-utility analyses of tobacco control interventions.
Shari P. Feirman, Allison M. Glasser, Lyubov Teplitskaya, David R. Holtgrave, David B. Abrams, Raymond S. Niaura, Andrea C. Villanti   +6 more
doaj   +1 more source

What can local authorities do to improve the social care-related quality of life of older adults living at home? Evidence from the Adult Social Care Survey [PDF]

, 2014
Local authorities spend considerable resources on social care at home for older adults. Given the expected growth in the population of older adults and budget cuts on local government, it is important to find efficient ways of maintaining and improving ...
van der Horst, H.E., Bosmans, J.E., Ostelo, R.W.J.G., Van Leeuwen, Karen, van der Horst, H E, Jansen, A.P.D., Malley, Juliette, Ostelo, R W, Jansen, A, Bosmans, J E, Netten, Ann, Netten, A., Bosmans, J.E.; id_orcid, Ostelo, R.W., van Leeuwen, K.M., Malley, J., Ostelo, R.W.J.G.; id_orcid   +16 more
core   +1 more source