Associations of Alzheimer's disease with inpatient hospital costs and with quality-adjusted life years: evidence from conventional and Mendelian randomization analyses in the UK Biobank. [PDF]
Dixon P, Anderson E.
europepmc +1 more source
Potential of predictive computer models for preoperative patient selection to enhance overall quality-adjusted life years gained at 2-year follow-up: a simulation in 234 patients with adult spinal deformity [PDF]
Tae-Min Oh +15 more
openalex +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Converting Evidence-Based Summary of Findings Evidence Tables Into Decision Analytical, Quality Adjusted Life Years (QALY) and Life Expectancies Metrics: A Tutorial. [PDF]
Hozo I, Guyatt G, Djulbegovic B.
europepmc +1 more source
Measuring the cost-effectiveness of treatments for people with multiple sclerosis: Beyond quality-adjusted life-years. [PDF]
Hawton A +6 more
europepmc +1 more source
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Total knee arthroplasty improves the quality-adjusted life years in patients who exceeded their estimated life expectancy. [PDF]
Palazzuolo M +3 more
europepmc +1 more source

