Measuring Quality-Adjusted Life-Years When Health Fluctuates [PDF]
Recurrent fluctuations in health states can occur as a result of long-term conditions with episodic symptoms or through side effects of cycles of treatment. Fluctuations and associated duration of symptoms can be predictable (eg, side effects of chemotherapy treatment) or unpredictable (eg, relapse in multiple sclerosis). Such recurrent fluctuations in
Sanghera, Sabina, Coast, Joanna
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Moderate-vigorous physical activity and health-related quality of life among Hispanic/Latino adults in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). [PDF]
BackgroundPhysical activity is a modifiable healthy behavior that has been shown to positively influence health-related quality of life. However, research examining the link between physical activity and health-related quality of life among Hispanic ...
Argos, Maria +17 more
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Descriptive Cost-Effectiveness Analysis of a Counseling and Coordination Model in Psychosocial Care. Integration of Health Care and Social Rehabilitation [PDF]
Introduction: A psychosocial outreach clinic was established to offer counseling and coordination of healthcare and complementary services for persons with psychosocial and mental problems. The cost-effectiveness of these services was measured based on a
Albrecht, Marion +8 more
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Cost-effectiveness of eplerenone in patients with systolic heart failure and mild symptoms [PDF]
Aim In the Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure (EMPHASIS-HF), aldosterone blockade with eplerenone decreased mortality and hospitalisation in patients with mild symptoms (New York Heart Association class II ...
Akehurst, R. +9 more
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[Background] As estimated by the World Health Organization, depressive disorders will be the leading contributor to the Global Burden of Disease by 2030.
Laura Ulbrich, Christoph Kröger
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Cost‐effectiveness analysis of delgocitinib in adult patients with atopic dermatitis in Japan
Objectives This study evaluated the cost‐effectiveness of delgocitinib relative to moisturization therapy in adult patients with moderate to severe atopic dermatitis. Methods The analysis was performed by using the simulation model with the patient‐level
Motoi Takenaka +7 more
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Quality-Adjusted Life-Years without Constant Proportionality [PDF]
A quality-adjusted life-year is a common unit of measurement in health valuation. Under its constant proportionality assumption, the value of a quality-adjusted life span is defined as the product of preference weight and life span.To empirically identify an alternative functional relationship between life span and value by relaxing the constant ...
Craig, Benjamin M. +3 more
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The Impact of Ankle Arthritis Treatment on Quality Adjusted Life Years
Category: Ankle, Ankle Arthritis Introduction/Purpose: Patients living with end stage ankle arthritis suffer significant disability. They are two standard deviations below population scores for all symptom and function SF-36 sub-scales. In addition, they
Kelly Hynes MD, BSc +5 more
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How to allocate scarce health resources without discriminating against people with disabilities [PDF]
One widely used method for allocating health care resources involves the use of cost-effectiveness analysis (CEA) to rank treatments in terms of quality-adjusted life-years (QALYs) gained.
John, Tyler M. +2 more
core +1 more source
Fundamental Measurement: The Need Fulfilment Quality of Life (N-QOL) Measure
The quality adjusted life year (QALY) has serious problems related to its failure to adhere to measurement theory. If a QALY is to be meaningful, the utility score that translates time spent to an equivalent time spent in so-called perfect health must ...
Paul C. Langley, Stephen P. McKenna
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