How to allocate scarce health resources without discriminating against people with disabilities [PDF]
One widely used method for allocating health care resources involves the use of cost-effectiveness analysis (CEA) to rank treatments in terms of quality-adjusted life-years (QALYs) gained.
John, Tyler M. +2 more
core +1 more source
Modelling the cost effectiveness of interferon beta and glatiramer acetate in the management of multiple sclerosis [PDF]
OBJECTIVE: To evaluate the cost effectiveness of four disease modifying treatments (interferon betas and glatiramer acetate) for relapsing remitting and secondary progressive multiple sclerosis in the United Kingdom. DESIGN: Modelling cost effectiveness.
Abrams, K. +6 more
core +2 more sources
Measuring Quality-Adjusted Life-Years When Health Fluctuates [PDF]
Recurrent fluctuations in health states can occur as a result of long-term conditions with episodic symptoms or through side effects of cycles of treatment. Fluctuations and associated duration of symptoms can be predictable (eg, side effects of chemotherapy treatment) or unpredictable (eg, relapse in multiple sclerosis). Such recurrent fluctuations in
Sanghera, Sabina, Coast, Joanna
openaire +4 more sources
Cost‐effectiveness analysis of delgocitinib in adult patients with atopic dermatitis in Japan
Objectives This study evaluated the cost‐effectiveness of delgocitinib relative to moisturization therapy in adult patients with moderate to severe atopic dermatitis. Methods The analysis was performed by using the simulation model with the patient‐level
Motoi Takenaka +7 more
doaj +1 more source
The relative value of different QALY types [PDF]
The oft-applied assumption in the use of Quality Adjusted Life Years (QALYs) in economic evaluation, that all QALYs are valued equally, has been questioned from the outset.
Bulfone, Liliana +6 more
core +2 more sources
Is increased hepatitis C virus case-finding combined with current or 8-week to 12-week direct-acting antiviral therapy cost-effective in UK prisons? A prevention benefit analysis [PDF]
UNLABELLED: Prisoners have a high prevalence of hepatitis C virus (HCV), but case-finding may not have been cost-effective because treatment often exceeded average prison stay combined with a lack of continuity of care. We assessed the cost-effectiveness
Brew, Iain F. +10 more
core +2 more sources
Willingness to Pay for a Quality-Adjusted Life-Year: The Individual Perspective [PDF]
The aim of this study was to elicit the individual willingness to pay (WTP) for a quality-adjusted life-year (QALY).In a Web-based questionnaire containing contingent valuation exercises, respondents valued health changes in five scenarios. In each scenario, the respondents first valued two health states on a visual analog scale (VAS) and expressed ...
Ana Bobinac +3 more
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Continence Across Continents To Upend Stigma and Dependency (CACTUS-D): study protocol for a cluster randomized controlled trial [PDF]
Background: Urinary incontinence occurs in 40 % of women aged 65 years and over; however, only 15 % seek care and many delay healthcare seeking for years.
Fritel, Xavier +6 more
core +1 more source
[Background] As estimated by the World Health Organization, depressive disorders will be the leading contributor to the Global Burden of Disease by 2030.
Laura Ulbrich, Christoph Kröger
doaj +1 more source
Putting the quality into quality-adjusted life years [PDF]
Over recent decades, a great deal of effort has been devoted towards developing instruments that can be used to elicit health state values. All of these instruments are conceptually very different from one another and all suffer from serious inherent biases.
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