Results 111 to 120 of about 20,140,975 (349)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Understanding Patterns of Care for Older Adults: Data to Action

open access: yesInternational Journal of Population Data Science
Objective Older adult population is growing rapidly, the current system is not adequately designed to meet the needs of individuals to live safely and independently in the place of their choice.
Beliz Acan Osman   +4 more
doaj   +1 more source

Assessing the Effects of Information System Quality and Relationship Quality on Continuance Intention in E-Tourism [PDF]

open access: gold, 2019
Ni Wayan Masri   +4 more
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Navigating Data Acquisition and Data Quality Validation of Large Databases: Practical Lessons

open access: yesInternational Journal of Population Data Science
Objective Have you ever been frustrated when working to acquire data? Have you experienced the trials and tribulations of readying data? ‘Best laid plans often go awry’.
Nedeene Hudema   +4 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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