Results 161 to 170 of about 4,993,523 (266)
Association between lifestyle values, lifestyle, and quality of life among the community-dwelling late middle-aged and older adults: A retrospective cross-sectional analysis. [PDF]
Bae S, Hong I, Kim AR.
europepmc +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Assessing image quality in photoacoustic imaging: A metric-based and deep learning-based evaluation. [PDF]
Van Der Brugge M, Francis KJ, Awasthi N.
europepmc +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Hydrochemical and GIS-based evaluation of groundwater suitability for irrigation using IWQI in the desert hinterland of western Nile Delta Egypt. [PDF]
Youssef YA +7 more
europepmc +1 more source

