Results 201 to 210 of about 20,140,975 (349)

Quality and content analysis of syphilis-related short videos on Douyin (TikTok): A cross-sectional study. [PDF]

Digit Health
Yang J, Zhao K, Liu J.
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Retracted: Multidimensional Attention-Based CNN Model for Identifying Apple Leaf Disease

Journal of Food Quality
Journal of Food Quality
doaj   +1 more source

Sustainability driven mechanism underlying crowdsourcing solvers' innovation behavior in the digital era evidence from SEM and fsQCA. [PDF]

Sci Rep
Jin X.
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Retracted: Empirical Analysis for Improving Food Quality Using Artificial Intelligence Technology for Enhancing Healthcare Sector

Journal of Food Quality
Journal of Food Quality
doaj   +1 more source

Habitat Quality Assessment Within Expanded Ranges of Dengue Vectors Using a Composite Index Scale. [PDF]

Ecol Evol
Naeem M, Zhu L, Bashir NH, Riasat M, Li W, Chen H.   +5 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Retracted: Integration of Artificial Intelligence and Blockchain Technology in Healthcare and Agriculture

Journal of Food Quality
Journal of Food Quality
doaj   +1 more source

Knee osteoarthritis health information on China's TikTok: a cross-sectional analysis of content quality and public health relevance. [PDF]

Front Digit Health
Ding Z, Wang J, Mao W, Yan Z, Zhong X, Du Y, Wu L.   +6 more
europepmc   +1 more source