Results 261 to 270 of about 20,140,975 (349)

The effect of dwelling size on the mental health and quality of life of female caregivers living in informal tiny homes in Hong Kong [PDF]

Crystal Ying Chan, Ruby Yuen Shan Lai, Becky Pek-Kei Hoi, Maggie Ying Yee Li, Joyce Ho Yi Chan, Henry Ho Fai Sin, Edwin Shun Kit Chung, Rowan Tak Yuen Cheung, Eliza Lai Yi Wong   +8 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Retracted: Multisensor Data and Cross-Validation Technique for Merging Temporal Images for the Agricultural Performance Monitoring System

Journal of Food Quality
Journal of Food Quality
doaj   +1 more source

The quality and reliability of short videos about migraine on Chinese social Media platforms (BiliBili and TikTok): A cross-sectional study. [PDF]

Digit Health
Qian S, Gu J, Zhao H.
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Retracted: Identifying Smart Strategies for Effective Agriculture Solution Using Data Mining Techniques

Journal of Food Quality
Journal of Food Quality
doaj   +1 more source

Multiomics transcriptome and metabolome insights into fat metabolism and meat quality in Songliao black pigs and Songlei crossbred pigs. [PDF]

BMC Genomics
Xu J, Zhang Y, Kumar ST, Liu E, Zheng Y, Zhu Y, Zhang Q, Sun WS, Pan L, Zhao Y, Zhang SM.   +10 more
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Retracted: A Novel Model to Detect and Classify Fresh and Damaged Fruits to Reduce Food Waste Using a Deep Learning Technique

Journal of Food Quality
Journal of Food Quality
doaj   +1 more source

Discovery of data quality issues in electronic health records: profound consequences for critical care medicine applications - a systematized review. [PDF]

Crit Care
de Andrade JBC, de Medeiros Cavalcante MAO, Lopes TLM, Treigher JMS, Balsells MD, Vasconcelos JL, Monteiro LC, da Silveira Mota DD.   +7 more
europepmc   +1 more source