Results 271 to 280 of about 20,140,975 (349)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Job quality and employee happiness: evidence from China. [PDF]

Front Psychol
Yu B, Song Z, Shen Z.
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Retracted: An Empirical Investigation in Analysing the Critical Factors of Artificial Intelligence in Influencing the Food Processing Industry: A Multivariate Analysis of Variance (MANOVA) Approach

Journal of Food Quality
Journal of Food Quality
doaj   +1 more source

Associations between socioeconomic status, dietary habits and health-related quality of life among children in rural riverside communities: the mediation role of food insecurity. [PDF]

Qual Life Res
de Lima Pereira L, Herkrath FJ, Siqueira JH, do Carmo Leal M, de Abreu FM, Lopes AF, Vettore MV.   +6 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Retracted: Blockchain-Based Secure Traceable Scheme for Food Supply Chain

Journal of Food Quality
Journal of Food Quality
doaj   +1 more source

The impact and mechanism effect of the digital divide on the quality of life of urban older adults patients with chronic diseases: Evidence from China. [PDF]

Digit Health
Chi Z, Lin L.
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Sleep and Quality of Life Before and After Surgery in Patients With Low-Grade Lumbar Spondylolisthesis. [PDF]

Med Sci Monit
Tunç B, Uzlu O, Şahin ÖF, Ünal E, Yılmaz A, Çağıl E.   +5 more
europepmc   +1 more source