Results 41 to 50 of about 25,701,198 (388)

Quality-filtering vastly improves diversity estimates from Illumina amplicon sequencing

open access: yesNature Methods, 2012
High-throughput sequencing has revolutionized microbial ecology, but read quality remains a considerable barrier to accurate taxonomy assignment and α-diversity assessment for microbial communities.
Nicholas A. Bokulich   +8 more
semanticscholar   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

« Quality is timeless » [PDF]

open access: yesEchoGéo, 2010
Illustration 1 - Entree du township de Khayelitsha, Cape Town, 2004 Auteur : Myriam Houssay-Holzschuch, 2004. La construction du township de Khayelitsha a ete decidee fin 1983 par P.W. Botha survolant en helicoptere la plaine sableuse a une trentaine de kilometres du centre ville du Cap (Houssay-Holzschuch, 1999).
openaire   +5 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Influence of Quality Improvement Activities and Direct Selling Through Mediated Partnership Model on Supply Chain, Farm-Gate Price and Indonesian Households Specialty Coffee Farmers' Income [PDF]

open access: yes, 2016
The low farm-gate price of agricultural commodities is commonly caused by low quality and complicated value chain. Quality improvement and direct selling through Mediated Partnership Model (Motramed) are conducted to increase farm-gate price and ...
Hartatri, D. F. (Diany)
core  

Requirements Quality Is Quality in Use [PDF]

open access: yesIEEE Software, 2019
The quality of requirements engineering artifacts is widely considered a success factor for software projects. Currently, the definition of high-quality or good RE artifacts is often provided through normative references, such as quality standards, textbooks, or generic guidelines. We see various problems of such normative references: (1) It is hard to
Henning Femmer, Andreas Vogelsang
openaire   +3 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

Egg Production and Physical Quality in Cortunix Cortunix Japonica Fed Diet Containing Piperine as Phytogenic Feed Additive [PDF]

open access: yes, 2015
The objective of this study was to determine the effect of piperine as a phytogenic feed additive on quail performances and egg quality. The experiment used a completely randomized design with five treatments and four replications and used ten quails ...
Astuti, D. A. (D)   +2 more
core   +1 more source

The Quality of Accruals and Earnings: The Role of Accrual Estimation Errors

open access: yes, 2002
This paper suggests a new measure of one aspect of the quality of working capital accruals and earnings.
Patricia M. Dechow, Ilia D. Dichev
semanticscholar   +1 more source

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