Results 41 to 50 of about 24,980,142 (412)

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

open access: yesFEBS Letters, EarlyView.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

Quality-filtering vastly improves diversity estimates from Illumina amplicon sequencing

open access: yesNature Methods, 2012
High-throughput sequencing has revolutionized microbial ecology, but read quality remains a considerable barrier to accurate taxonomy assignment and α-diversity assessment for microbial communities.
N. Bokulich   +8 more
semanticscholar   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Quality of Institutions, Technological Progress, and Pollution Havens in Latin America. An Analysis of the Environmental Kuznets Curve Hypothesis [PDF]

open access: yes, 2019
A set of 17-year panel data (1996–2013) across a representative sample from eighteen Latin American countries is used to respond four research questions: Did Latin American Greenhouse Gas (GHG) emissions prove the Environmental Kuznets Curve (EKC ...
Cansino Muñoz-Repiso, José Manuel   +2 more
core   +1 more source

Sensory Qualities, Sensible Qualities, Sensational Qualities [PDF]

open access: yes, 2009
Abstract In theorizing about perception philosophers have often multiplied qualities. To perceptible qualities of external objects, like colours and shapes (‘sensible’ qualities), have been added qualities of experiences (‘sensory’ qualities) or of sense-data (‘sensational’ qualities). This article starts with sensory qualities.
openaire   +4 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

« Quality is timeless » [PDF]

open access: yesEchoGéo, 2010
Illustration 1 - Entree du township de Khayelitsha, Cape Town, 2004 Auteur : Myriam Houssay-Holzschuch, 2004. La construction du township de Khayelitsha a ete decidee fin 1983 par P.W. Botha survolant en helicoptere la plaine sableuse a une trentaine de kilometres du centre ville du Cap (Houssay-Holzschuch, 1999).
openaire   +6 more sources

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Price competition with uncertain quality and cost [PDF]

open access: yesarXiv, 2019
Consumers in many markets are uncertain about firms' qualities and costs, so buy based on both the price and the quality inferred from it. Optimal pricing depends on consumer heterogeneity only when firms with higher quality have higher costs, regardless of whether costs and qualities are private or public.
arxiv  

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