Results 51 to 60 of about 25,431,948 (353)
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
My Home Life: promoting quality of life in care homes [PDF]
, 2012 A new report from JRF outlines the findings from the My Home Life project. My Home Life is a collaborative initiative between Age UK, City University, the Joseph Rowntree Foundation and Dementia UK promoting quality of life in care homes.
Meyer, J., Owen, T.
core
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Quality Standards for the Development, Application, and Evaluation of Measurement Instruments in Social Science Survey Research [PDF]
, 2015 [Introduction] Since its establishment in 2004, the German Data Forum (RatSWD), which is funded by the German Federal Ministry of Science and Research (BMBF), has been advising the federal government and the governments of the federal states (Länder) on ...
Quality Standards Working Group
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Quality of Medical Information Determine the Quality of Diagnosis Code [PDF]
, 2019 The accuracy of the diagnosis code has implications for future patient care planning, provision of health services and patient care costs. Therefore, this study has analyzed the influence of the quality of medical information on the quality of the ...
Ismayani, A. (Ani) +2 more
core +3 more sources
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Quality: who’s quality? Developing, supporting and sustaining high quality social work services [PDF]
, 2011 An examination of "Quality in Social Work Services" as a contested concept. The author proposes a 'whole systems' model of developing, defining, distinguishing and sustaining the notion of 'Quality".
Croft, Adrian
core
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
Quality of Root Canal Obturation Performed by Senior Undergraduate Dental Students [PDF]
, 2015 The aim of the present study was to assess the quality of canal obturation performed by undergraduate denal students at Saveetha Dental College and Hospitals, Chennai.
Nagaraja, S. (Sundahnath)
core