Results 251 to 260 of about 18,119,282 (331)

Prostate Cancer Patient‐Derived Organoids (PDOs) as Functional Avatars for Antisense Oligonucleotide (ASO)‐Based Personalized Therapy

Advanced Healthcare Materials, EarlyView.
Prostate patient‐derived organoids (PDOs) were established from TURP and biopsy specimens with >90% success and retain key features of their tissues of origin, making them functional avatars for antisense oligonucleotide (ASO) therapy . Transfecting single cells outside the Matrigel matrix and then reconstituting organoids overcomes the 3D delivery ...
Thi Thom Tran, Thi Tu Uyen Phan, Michael Baboudjian, Quang Hieu Duong, Ines Sousa, Thi Thuy Le, Virginie Baylot, Sophie Giusiano, Laurent Daniel, Pauline Brige, Benjamin Guillet, Cyrille Bastide, Carmen Garrido, David Taïeb, Thi Khanh Le, Palma Rocchi   +15 more
wiley   +1 more source

The Role of Viscoelasticity in Heterogeneous Glioblastoma Stem Cell Invasion in Biomimetic 3‐Dimensional Hydrogels

Advanced Healthcare Materials, EarlyView.
The role of viscoelasticity in the invasion of heterogeneous glioblastoma stem cells (GSCs) was investigated with GSCs categorized into subgroups based on molecular profile, as Reactive, Invasive, or Constructive using viscoelastic biomimetic hyaluronan‐oxime hydrogels.
Nicole J. Blaine, Arianna Skirzynska, Allysia A. Chin, Julie Audet, Molly S. Shoichet   +4 more
wiley   +1 more source

Hand and shoulder diagnoses are associated with substantial bodily pain compared to vascular complications and long-term glycaemic control in people with long-term type 1 diabetes. [PDF]

J Patient Rep Outcomes
Molvær AK, Memelink IM, Igland J, Peyrot M, Tell GS, Berg TJ.   +5 more
europepmc   +1 more source

Economic burden and quality of life of IgG4-related disease in China: A comparative analysis of three treatment regimens. [PDF]

Rheumatol Immunol Res
Wang Y, Jiang J, Nie Y, Li J, Zhang J, Luo Q, Yang X, Zhang N, Liu S, Lei J, Zhou J, Fei Y, Peng L, Zhang W.   +13 more
europepmc   +1 more source

Survival and Functional Status Outcomes in Heart Transplant Recipients: An Analysis of Organs From Donors Who Overdosed. [PDF]

Clin Transplant
Siebert JL, Mendez JD, Yost J, Bernhardt PW.   +3 more
europepmc   +1 more source

US population-level model of clinical impact of lorlatinib treatment on ALK+ metastatic non-small cell lung cancer outcomes. [PDF]

J Comp Eff Res
Kasle A, Abrahami D, Veenstra D, Morlock R, Ramachandran P, Stansfield L, Mak R.   +6 more
europepmc   +1 more source