Results 201 to 210 of about 4,106,389 (268)

Quality analysis of photometers using vertical window illuminance measurements. [PDF]

Sci Rep
Tabaka P, Ściężor T.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Quality Analysis of YouTube-Based Exercise Programs for Typically Developing Children: Content Analysis. [PDF]

Healthcare (Basel)
Hong J, Do Y, Rha DW, Kim NY.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

YouTube as an information source in deep margin elevation: Reliability, accuracy and quality analysis. [PDF]

PLoS One
Ozdemir ZM, Yavuz SA, Gursel Surmelioglu D.   +2 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Moderate methodological quality in the 50 most cited studies on meniscus root tears: A bibliometric study and methodological quality analysis. [PDF]

J Exp Orthop
Vieider RP, Hughes JD, Lesniak BP, Kolevar M, Wackerle AM, Dias K, Grandberg C, Musahl V.   +7 more
europepmc   +1 more source

Evaluation of Large Language Models in Tailoring Educational Content for Cancer Survivors and Their Caregivers: Quality Analysis. [PDF]

JMIR Cancer
Liu D, Hu X, Xiao C, Bai J, Barandouzi ZA, Lee S, Webster C, Brock LU, Lee L, Bold D, Lin Y.   +10 more
europepmc   +1 more source

Exploring the Frontiers of Food Science: A Comprehensive Review of Advanced Magnetic Resonance Applications in Food Analysis, Quality Analysis, and Safety Assessment. [PDF]

Food Sci Nutr
Alkanan ZT, Altemimi AB, Awlqadr FH, Alkaisy QH, Hashemi SMB, Pratap-Singh A.   +5 more
europepmc   +1 more source

Yield and nutritional quality analysis in Brassica pekinensis: Regulation of different nitrogen forms. [PDF]

Food Chem X
Mao L, Wei B, Tie J, Gao X, Wang X, Yang J, Dawuda MM, Yu J, Hu L.   +8 more
europepmc   +1 more source