Results 51 to 60 of about 4,106,389 (268)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Do international standards influence the development of smart regions and cities? [PDF]

open access: yesZbornik radova Ekonomskog fakulteta u Rijeci : časopis za ekonomsku teoriju i praksu, 2019
The growth of city population has consequences on the sustainability and development of smart regions. International standards can provide good practices in wide areas related to environmental, security and social aspects that contribute to the
Jelena Ruso   +2 more
doaj   +1 more source

Dimensional Analysis of Airline Quality [PDF]

open access: yesInterfaces, 2004
Dimensional analysis is widely used in physics and engineering to contribute to modeling systems in which variables are measured in incompatible units. I used dimensional analysis to rank the airlines in overall quality based on US Department of Transportation data: on-time arrivals, denied boardings, mishandled baggage, and customer complaints.
openaire   +1 more source

Provenance analysis: Towards quality provenance [PDF]

open access: yes2012 IEEE 8th International Conference on E-Science, 2012
Data provenance, a key piece of metadata that describes the lifecycle of a data product, is crucial in aiding scientists to better understand and facilitate reproducibility and reuse of scientific results. Provenance collection systems often capture provenance on the fly and the protocol between application and provenance tool may not be reliable. As a
You-Wei Cheah, Beth Plale
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A New Validated RP- HPLC Method for the Determination of Nevirapine in Human Plasma

open access: yesE-Journal of Chemistry, 2010
A rapid, selective and sensitive high performance liquid chromatographic method for the estimation of nevirapine in human plasma has been developed. Chromatography was carried out on a Hypersil BDS C18 column using a mixture of ammonium acetate buffer ...
C. H. Venkata Kumar   +2 more
doaj   +1 more source

Taxes and quality: A market–level analysis [PDF]

open access: yesAustralian Journal of Agricultural and Resource Economics, 2002
A conventional assumption of product homogeneity when the commodity of interest is actually heterogeneous will lead to errors in an analysis of the incidence of policies, such as taxes. In this article, an equilibrium displacement model is used to derive analytical solutions for price, quantity, and quality effects of ad valorem and per unit taxes. The
James, Jennifer S., Alston, Julian M.
openaire   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Validated Spectrophotometric Methods for the Determination of Mycophenolate: An Anti-Neoplastic Agent in Bulk and Pharmaceutical Dosage Forms

open access: yesJournal of Chemistry, 2013
Three simple, precise and cost-effective spectrophotometric methods have been developed for the determination of Mycophenolate in bulk and its pharmaceutical formulations. Mycophenolate shows 𝜆max at 250.0 nm in zero-derivative spectrum (method A), 258.0 
A. Narendra   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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