Results 141 to 150 of about 41,998 (282)

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source

Urgent ERCP performed with single-use duodenoscope (SUD) in patients with moderate-to-severe cholangitis: Single-center prospective study

Endoscopy International Open
Graziella Masciangelo, Paolo Cecinato, Igor Bacchilega, Michele Masetti, Rodolfo Ferrari, Rocco Maurizio Zagari, Bertrand Napoleon, Romano Sassatelli, Pietro Fusaroli, Andrea Lisotti   +9 more
doaj   +1 more source

Drainage of walled-off necrosis: when can I still use plastic stents?

Endoscopy International Open, 2023
Mark Topazian
doaj   +1 more source

River transport of cattle in northern Brazil - a systematic review. [PDF]

Trop Anim Health Prod
da Silva WC, Rebelo da Silva ÉB, Ferreira de Souza IM, Pinto VS, Paixão Vilela LG, Lima Sousa CE, da Silva TN, Silva Souza AD, de Sousa Cunha JP, Gomes de Castro VC, Colares Camargo-Júnior RN, de Andrade RL, de Lima JS, Ximenes Silva LK, Maciel E Silva AG, Brito Lourenço Júnior J, Rodrigues da Silva JA, Nadai Bonin Gomes M, de Araújo CV.   +18 more
europepmc   +1 more source

ZDHHC18‐Mediated Palmitoylation of ORF3a Promotes SARS‐CoV‐2 Pathogenesis by Antagonizing TRIM16‐Mediated Ubiquitination and Proteasomal Degradation

Advanced Science, EarlyView.
Palmitoylation by ZDHHC18 blocks ORF3a K27‐linked ubiquitination mediated by TRIM16, thereby preventing its proteasomal degradation and strengthening viral pathogenesis. Targeting palmitoylation through a pharmacological inhibitor (2‐BP), a competitive inhibitory peptide (OPIP), or adenovirus‐mediated knockdown of ZDHHC18 expression presents a ...
Sidi Yang, Kun Li, Lihong Liu, Linsen Zeng, Qifeng Deng, Jiacheng Huang, Xiaoran Dong, Xin Wang, Jianwei Liang, Hongchao Liu, Hong Peng, Yuxin Lin, Xiaolu Xie, Yuzhen Ye, Tiefeng Xu, Zhaohuan Wang, Chun‐Mei Li, Deyin Guo   +17 more
wiley   +1 more source

Water exchange technique improves colonoscopy in patients with spinal cord injury: Results of a matched cohort study

Endoscopy International Open
Thorsten Brechmann, Mirko Aach, Thomas A. Schildhauer, Dennis Grasmücke   +3 more
doaj   +1 more source

Logistical Challenges in Platform Randomized Trials - Operational Realities That Curb the Promise of Efficiency. [PDF]

Clin Epidemiol
Thorlund K, Park JJH, Wise MP, Doleman B, Petersen JJ, Lange T, Mathiesen O, Skrifvars MB, Saxena M, Nielsen N, Mills EJ, Grand J, Jakobsen JC.   +12 more
europepmc   +1 more source

Tunable Dynamics via Dual‐Ion Modulation for Event‐based Data Processing Using a Highly Uniform and Self‐Rectifying Memristor Array

Advanced Science, EarlyView.
Tunable dynamics of an interface‐type memristor array enabled by dual‐ion modulation through Ag nanoclusters are demonstrated. A 32 × 32 one‐resistor (1R) array exhibits 100% yield with high temporal/spatial uniformity (<3%) and a rectification ratio of 105.
Yoonho Cho, Dawon Kim, Jeonghong Lee, Dae‐won Kim, See‐On Park, Jongmin Bae, Taehwan Jang, Shinhyun Choi   +7 more
wiley   +1 more source

Effect of virtual reality distraction on anxiety, pain and discomfort during unsedated gastroscopy: Randomized controlled trial

Endoscopy International Open
Zita Bouman, Froukje De Vries, Mattanja De Ruiter, Anneloes Bakker, Adriaan CITL Tan   +4 more
doaj   +1 more source

Application of process mining in healthcare logistics: a systematic literature review protocol. [PDF]

BMJ Open
Murazzano L, Landa P, Ghafourian Nasiri M, Bergeron F, Côté A.   +4 more
europepmc   +1 more source