Results 61 to 70 of about 6,418,185 (279)

Evaluation of the effectiveness of hip and knee implant models used in Catalonia: a protocol for a prospective registry-based study

open access: yesJournal of Orthopaedic Surgery and Research, 2019
Background Monitoring results regarding the effectiveness of knee and hip arthroplasties may be useful at the clinical, economic and patient level and help reduce the number of prosthesis revisions.
Jorge Arias-de la Torre   +9 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Patterns of Frailty in Newly Diagnosed Older Patients With Nonvalvular Atrial Fibrillation Initiating Oral Anticoagulation

open access: yesJCSM Communications
Background Frailty is a significant predictor of death in patients with atrial fibrillation (AF), with the frailty index (FI) acting as an effective severity classification tool.
Ryo Nakamaru   +7 more
doaj   +1 more source

Quality assessment by science teachers: Five focus areas [PDF]

open access: yes, 2013
In order to teach science well, science teachers need to know what to focus on in order to ensure their assessment of student learning is meaningful and useful for the students’ on going learning and development.
Edwards, Frances
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Peptidomic Analysis of Potential Bioactive Peptides in Mare Milk Under Different Heat Treatment Conditions

open access: yesFoods
Active peptides in mare milk have unique biological activities, but how the bioactive protein in mare’s milk changes under the influence of temperature has not been fully studied.
Xiaoxiao Lou   +6 more
doaj   +1 more source

Nutritional value and coagulation properties of milk from local cow breeds, including the selected macro- and micronutrients and trace elements

open access: yesMljekarstvo, 2020
The aim of the study was to assess the nutritional value of milk based on its chemical composition and content of selected minerals and to determine the coagulation properties of raw milk from native Polish breeds, i.e.
Anna Teter   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Using Multilevel Mediation Model to Measure the Contribution of Beliefs to Judgments of Learning

open access: yesFrontiers in Psychology, 2020
Recent studies on judgments of learning (JOLs) suggest that beliefs play an important role in the formation of JOLs. The current article introduces a multilevel mediation model to quantify the contribution of beliefs to JOL formation when both JOLs and ...
Xiao Hu   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy