Results 81 to 90 of about 222,384 (292)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Situational Strategic Planning in primary care: troubleshooting and reinventing actions [PDF]

Revista Brasileira em Promoção da Saúde, 2009
Objective: To apply the Strategic Situational Planning (SSP) in a problem selected by the Family Health team, aiming at proposing intervention strategies to correct this deficiency.
Ariane Graças de Campos
doaj  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Common Foreign Quality Evaluation Tools of Primary Health Care and Their Implications for China [PDF]

Zhongguo quanke yixue
Primary health care (PHC) is the bottom of the health care system, and its quality not only relates to the construction of hierarchical medical system, but also affects the health level of residents. Scientific and reasonable evaluation of PHC quality is
LIU Lidi, LIAO Xiaoyang, ZHAO Qian, GUO Yiming, WEN Yuqi, LIU Changming, FANG Xiang
doaj   +1 more source

Patient satisfaction and quality of care of the internal medicine service of Hospital Daniel Alcides Carrión. Huancayo - Perú

Revista de la Facultad de Medicina Humana, 2020
Introduction: Patient satisfaction is an indicator of the quality of care provided in health services.Knowing the level of satisfaction will improve deficiencies and reaffirm strengths to develop a healthsystem that provides the quality care that ...
Richard J. Febres-Ramos, Miguel R. Mercado-Rey   +1 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Begriffe und Konzepte des Qualitätsmanagements – 4. Auflage

GMS Medizinische Informatik, Biometrie und Epidemiologie, 2018
Quality and safety of healthcare have become key concepts during the last two decades on both national and international levels. In Germany this target of healthcare policy is currently regulated by a cascade of legal requirements and directives: all ...
Sens, Brigitte, Pietsch, Barbara, Fischer, Burkhard, Hart, Dieter, Kahla-Witzsch, Heike Anette, von Friedrichs, Verena, Nothacker, Monika, Paschen, Ulrich, Rath, Sabine, Rode, Susanne, Schneider, Kyra, Schrappe, Matthias   +11 more
doaj   +1 more source

Evaluation of Participant Patient Satisfaction Evaluation in Childbirth Care at Independent Midwifery Practices

Jurnal Ners dan Kebidanan Indonesia, 2020
Patient satisfaction is a measure of the quality of care. One important problem that continues to be faced is the lack of good quality service and getting client satisfaction.
Dwie Ayu
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source