Results 71 to 80 of about 1,092,913 (352)

Quality comparability analysis on production site change of human coagulation factor Ⅷ

Zhongguo shuxue zazhi
Objective To study the quality comparability of human coagulation factor Ⅷ (FⅧ) produced before and after the change of factory site. Methods A comparative study was carried out on quality quantitative indexes, related impurities and stability data of FⅧ
TIAN Tianli, WANG Hanyu, MA Yiyun, XUE Wei, ZHANG Shengchao, ZHANG Yaoyin, ZHOU Shunbo, ZOU Lingling, CHEN Chuan, DING Yaling   +9 more
doaj   +1 more source

Comprehensive Review of Analytical Methods for Quantifiable Estimation of Gliptins, Including Metformin, in Pharmaceutical and Bulk Dosage Forms [PDF]

E3S Web of Conferences
Insufficient insulin secretion or action leads to diabetes mellitus, causing chronic hyperglycemia and metabolic abnormalities. Metformin is a common medication recommended as first-line treatment for Type 2 DM, aiming to prevent complications and early ...
Dhruv Ashwini P., Vyas Dr. Amit kumar J.
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Red, green, and blue model assessment and AQbD approach to HPTLC method for concomitant analysis of metformin, pioglitazone, and teneligliptin

Future Journal of Pharmaceutical Sciences
Background The CDSCO of India has authorized a combination of metformin hydrochloride, teneligliptin hydrochloride, and pioglitazone hydrochloride for the treatment of insulin-independent diabetes.
Pintu Prajapati, Pooja Patel, Dhrumi Naik, Anzarul Haque, Shailesh Shah   +4 more
doaj   +1 more source

Weighing the costs: Implementing the SLMTA programme in Zimbabwe using internal versus external facilitators

African Journal of Laboratory Medicine, 2014
Background: In 2010, the Zimbabwe Ministry of Health and Child Welfare (MoHCW) adopted the Strengthening Laboratory Management Toward Accreditation (SLMTA) programme as a tool for laboratory quality systems strengthening.
Edwin Shumba, Phoebe Nzombe, Absolom Mbinda, Raiva Simbi, Douglas Mangwanya, Peter H. Kilmarx, Elizabeth T. Luman, Sibongile N. Zimuto   +7 more
doaj   +1 more source

Chapter 9: Quality Assurance [PDF]

, 2000
The OTiS (Online Teaching in Scotland) programme, run by the now defunct Scotcit programme, ran an International e-Workshop on Developing Online Tutoring Skills which was held between 8–12 May 2000.

core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Box–Behnken design assisted HPTLC method for quantification of teneligliptin hydrobromide hydrate, metformin hydrochloride and pioglitazone hydrochloride in pharmaceutical dosage form

Discover Chemistry
A Design of expert approach was used to develop and validate a high-performance thin layer chromatography method for simultaneously determining Teneligliptin hydrobromide hydrate, Metformin hydrochloride, and Pioglitazone hydrochloride in tablets.
Patel Kalpana, Babariya Raj, Shah Hitaxi, Tandel Devang, Patel Subhashchandra, Gandhi Tejal   +5 more
doaj   +1 more source

Measuring Scientific Misconduct—Lessons from Criminology

Publications, 2014
This article draws on research traditions and insights from Criminology to elaborate on the problems associated with current practices of measuring scientific misconduct. Analyses of the number of retracted articles are shown to suffer from the fact that
Felicitas Hesselmann, Verena Wienefoet, Martin Reinhart   +2 more
doaj   +1 more source

Quality control of the traditional herbs and herbal products: a review

Future Journal of Pharmaceutical Sciences, 2020
Background Herbal medicinal material and product need is increasing, and with this increase in the need, it is very much an essential requirement to maintain the quality of them.
Amruta Balekundri, Vinodhkumar Mannur
doaj   +1 more source