Results 91 to 100 of about 840,586 (306)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

IMPLEMENTASI SISTEM PENJAMINAN MUTU SEKOLAH PADA SMPN 25 B. LAMPUNG

open access: yesJurnal E-DuMath, 2016
In globalization era, quality has related to work which produces goods and service. School is organization that produces service. In order to obtain qualified school, it needs quality of human resources such the head master, teachers, and staff.
Tri Yuni Hendrowati
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Blockchain-Based Quality Assurance System for Academic Programs

open access: yesApplied Sciences
Nowadays, technology is increasingly being adopted in different kinds of businesses to process, store, and share sensitive information in digital environments that include enormous numbers of users.
Mohammad Alkhatib   +2 more
doaj   +1 more source

Internal quality assurance system of higher education: experience of the Republic of Poland

open access: yesОсвітологія, 2018
The article analyzes the higher education institutions activities of the Republic of Poland in order to identify the perspective directions of the use of Polish experience in quality assurance in Ukraine.
Hryshchuk Yuliia
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Quality Assurance System at Primary Level of Healthcare [PDF]

open access: yesIzzivi Prihodnosti, 2018
Purpose: Purpose of the research is to clarify the basis, development and the state of the art of quality assurance systems at primary level of healthcare.
Suzana Šuklar
doaj  

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