Results 101 to 110 of about 2,630,584 (353)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Spacelab Data Processing Facility (SLDPF) quality assurance expert systems development [PDF]

open access: yes
The Spacelab Data Processing Facility (SLDPF) is an integral part of the Space Shuttle data network for missions that involve attached scientific payloads.
Basile, Lisa R., Kelly, Angelita C.
core   +1 more source

A Study of Quality Assurance Practices in the Universiti Sains Malaysia (USM), Malaysia [PDF]

open access: yes, 2001
This article looks at the quality assurance practices amongst three (3) groups of staff in the School of Distance Education, Universiti Sains Malaysia, i.e. lecturers, resident tutors and support staff.
Idrus, Rozhan M., Khoo, Helen Chooi Sim
core  

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Governance Reform of German food safety regulation: Cosmetic or real? [PDF]

open access: yes
Discussion of institutional changes made by the German government in response to the emergence of the first cases of BSE in Germany in 2000. Due to the establishment of a large-scale private sector quality assurance scheme, regulation moved away from ...
Steiner, Bodo
core   +1 more source

A Next Generation of Quality Assurance Models : On Phases, Levels and Circles in Policy Development [PDF]

open access: yes, 2001
Quality assessment has been part of the feedback mechanisms of European higher education systems since around 1980. Due to internal dynamics, `erosion¿ of the effectiveness of firstgeneration quality assessment systems has led to loss of credibility ...
Jeliazkova, Margarita   +1 more
core   +1 more source

Quality systems in Dutch health care institutions [PDF]

open access: yes, 1997
The implementation of quality systems in Dutch health care was supervised by a national committee during 1990-1995. To monitor the progress of implementation a large survey was conducted in the beginning of 1995.
Bakker, D.H. (Dinny) de   +3 more
core   +5 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

QUALITY STANDARDS FOR DISTANCE LEARNING IN HIGHER EDUCATION: A COMPARATIVE ANALYSIS OF CANADIAN AND RUSSIAN PRACTICES

open access: yesОбразование и наука, 2015
The aim of the investigation is to perform comparative analysis of the quality assessment and policies of quality assurance in postsecondary education in Canada and Russian Federation.Methods.
Natalia V. Buhanova   +3 more
doaj   +1 more source

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