Results 171 to 180 of about 29,176,109 (398)

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Mitochondrial quality control in kidney injury and repair

open access: yesNature Reviews Nephrology, 2020
Chengyuan Tang   +5 more
semanticscholar   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

PERANCANGAN DAN IMPLEMENTASI QUALITY METRIC MENGGUNAKAN METODE INTERNAL CONTROL UNTUK CONTROL QUALITY PADA PROYEK E-LEARNING UNIVERSITAS X [PDF]

open access: yes, 2019
ABSTRAK Universitas X merupakan perguruan tinggi swasta yang sedang mengembangkan sistem pembelajaran berbasis e-learning. Proyek e-learning terbagi menjadi 4 program besar yaitu pengembangan konten digital, pengembangan studio produksi, pengembangan ...
FAUZI ILHAM SOPWANDI
core  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Evaluation of the feasibility, appropriateness, and acceptability of an environmental cleaning program improvement toolkit at a tertiary care hospital in Nigeria

open access: yesAntimicrobial Resistance and Infection Control
Background Environmental cleaning is a key infection prevention and control (IPC) intervention in healthcare settings. The U.S. Centers for Disease Control and Prevention (CDC), with Infection Control Africa Network (ICAN), developed best practices for ...
Cori Dennison   +8 more
doaj   +1 more source

A Comprehensive Investigation of Lipid Profile During the Solid-State Fermentation of Rice by Monascus purpureus

open access: yesFoods
Red yeast rice is a nutraceutical fermented product used worldwide for the symptomatic relief of dyslipidemia and cardiovascular disease. However, the fermentation-induced lipid transformation from rice to red yeast rice remains unclear. Herein, an ultra-
Lan Lan   +8 more
doaj   +1 more source

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