Results 71 to 80 of about 8,868,357 (351)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Factors influencing sepsis associated thrombocytopenia (SAT): A multicenter retrospective cohort study.

PLoS ONE
IntroductionSepsis associated thrombocytopenia (SAT) is a common complication of sepsis. We designed this study to investigate factors influencing SAT.MethodsPatients with sepsis (2984 in Peking union medical college hospital [PUMCH] database, 13165 in ...
Lu Wang, Jieqing Chen, Xiang Zhou, China National Critical Care Quality Control Centre Group (China-NCCQC)   +3 more
doaj   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Assessment of the impact of procurement centralization on the drug provision for patients within the High-Cost Nosology Program in the Russian Federation

Фармакоэкономика
Background. In the Russian Federation, patients receive expensive drugs from the federal budget funds within High-Cost Nosology (HCN) Program.Objective: to assess the impact of drug procurement centralization on the weighted average price (WAP) per 1 ...
V. V. Omelyanovskiy, V. A. Ryagina, A. G. Kharitonova, K. I. Matrenin, A. A. Kingshott, O. V. Ashikhmina, M. V. Zhirov   +6 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Manufacture and quality control of interconnecting wire harnesses [PDF]

, 1973
Four-volume series of documents has been prepared as standard reference. Each volume may be used separately and covers wire and cable preparation as well as harness fabrication and installation.

core   +1 more source

Economic analysis of implementing Systemic Coronary Risk Estimation (SCORE2) scale and long-term consequences

Фармакоэкономика
Objective: to assess the demand for pharmacotherapy in risk groups on adverse cardiovascular (CV) events identified during prophylactic medical examination of the adult population according to the SCORE2 (Systemic Coronary Risk Estimation) scale, which ...
E. O. Kurilovich, A. V. Nikitina, I. V. Sorokovikov   +2 more
doaj   +1 more source

Review: Policy strategy of nano cosmetic testing in Indonesia [PDF]

Pharmacia
The implementation of nanotechnology in the cosmetic industry has developed promptly in recent decades. Among them are sunscreen, skincare, decorative makeup, and hair colorant.
Yustina Yustina, Nany Bodrorini, Alfi Sophian, Endang Lukitaningsih   +3 more
doaj   +3 more sources

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Robust scheduled control of longitudinal flight with handling quality satisfaction [PDF]

, 2011
Classic flight control systems are still widely used in the industry because of acquired experience and good understanding of their structure. Nevertheless, with more stringent constraints, it becomes difficult to easily fulfil all the criteria with ...
Akhrif, Ouassima, Bérard, Caroline, Saussié, David, Saydy, Lahcen   +3 more
core   +1 more source