Results 91 to 100 of about 9,335,776 (306)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Distributed Queries for Quality Control Checks in Clinical Trials [PDF]

open access: yes, 2011
Operational Quality Control (QC) checks are standard practice in clinical trials and ensure ongoing compliance with the study protocol, standard operating procedures (SOPs) and Good Clinical Practice (GCP).
Brinkley, James F   +3 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Ontological quality control in large-scale, applied ontology matching [PDF]

open access: yes, 2013
To date, large-scale applied ontology mapping has relied greatly on label matching and other relatively simple syntactic features. In search of more holistic and accurate alignment, we offer a suite of partially overlapping ontology mapping heuristics ...
Legg, Catherine, Sarjant, Samuel
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Food safety knowledge, attitudes, and practices among fish vendors in Cumilla, Bangladesh

open access: yesDiscover Food
Food safety knowledge and practices are essential to prevent contamination, reduce health risks, and ensure the overall quality and safety of food products, particularly in perishable goods like fish.
Abdullah Al Mizan   +4 more
doaj   +1 more source

Instruction manuals for liquid penetrant nondestructive testing [PDF]

open access: yes, 1969
Manuals provide quality control and test personnel with basic information on liquid penetrant testing. Topics covered include scope of application, equipment and materials used, test procedures, safety precautions, quality control, and comparison of ...

core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Weight Control Strategies and Diet Quality [PDF]

open access: yes
obesity, diet quality, nhanes, Consumer/Household Economics, Food Consumption/Nutrition/Food Safety, I00,
Gao, Zhifeng   +2 more
core   +1 more source

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