Results 91 to 100 of about 1,742,858 (300)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Management control for quality in a hospitality business using ARP curves and the multivariate geometric indicator - Control de gestión para la calidad en una empresa hotelera con curvas ARP y el indicador geométrico multivariante

open access: yesSuma de Negocios
Introducción / Objetivo: este estudio tiene como objetivo evaluar la calidad del servicio en una empresa hotelera que opera con tres líneas de atención: preferencial, estándar y básica, bajo condiciones cambiantes.
Tomás José Fontalvo Herrera   +2 more
doaj   +1 more source

On the quality indicators of automated control systems software

open access: yesПрограммные системы и вычислительные методы, 2020
The subject of the research is the process of developing automated control systems software. The object of the research is the quality control system of this process. The regulatory documents establish a list of the main characteristics of program quality assessment, which, as practice has shown, does not fully meet its purpose, providing not ...
openaire   +1 more source

High quality indoor environments for sustainable office buildings [PDF]

open access: yes, 2008
The quality of office indoor environments is considered to consist of those factors that impact occupants according to their health and well-being and (by consequence) their productivity.
Brown, Stephen K
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Illumina FASTQ files - Read Segment Quality Control Indicator

open access: yes, 2010
In another quirk to the FASTQ story, recent Illumina FASTQ files don't actually use the full range of PHRED scores - and a score of 2 has a special meaning, <em> The Read Segment Quality Control Indicator </em> (RSQCI, encoded as 'B'). Hats off to <em> Dr Torsten Seemann </em> for raising awareness of this issue in his post on ...
openaire   +2 more sources

THE STRUCTURE OF FARMERS' PERCEPTIONS OF GROUND WATER POLLUTION [PDF]

open access: yes
Data from a 1992 Georgia Farm Practices survey are used to examine the structure of farmers' perceptions of ground water pollution and their support of regulations to protect ground water.
Elnagheeb, Abdelmoneim H.   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

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