Results 111 to 120 of about 16,019,502 (257)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Quality control and improvement of structural timber
, 2010 Modern applications of structural timber like e.g. in the field of multi-storey domiciles or large span structures require graded timber products with sufficient and in many cases high performing mechanical properties.
Köhler, J. (author) +2 more
core +1 more source
Presumpscot River Basin - Cumberland County Tidewater Water Quality Management Plan [PDF]
, 1976 Presumpscot River Basin - Cumberland County Tidewater Water Quality Management Plan Maine Department of Environmental Protection, Bureau of Water Quality Control, Division of Water Quality Evaluation and Planning, August, Maine (June 1976).
Bureau of Water Quality Control
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Encl 10 401 Water Quality Certification
Water Boards Water Boards KRI STINE MURRAY, CHAIR I JAYNE J o y, EXECUTIVE OFFICER e GAVIN N EWSOM GOVfA NOR YANA GARCIA SECRETARY FOR ENVIRONMENTAL PROTECTION 3737 Main Street, Suite 500, Riverside, CA 92501-3348 I www.waterboards.ca.gov/santaana Santa ...
California. State Water Quality Control Board;
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Involving patients in quality indicator development – a systematic review
, 2013 Thomas Kötter,1,2 Friederike Anna Schaefer,2 Martin Scherer,2 Eva Blozik1,2 1Institute for Social Medicine and Epidemiology, University of Lübeck, Lübeck, Germany; 2Department of Primary Medical Care, University Medical Center Hamburg ...
Kötter T +3 more
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Los Angeles Regional Water Quality Control Board Minutes - February 19, 2002
, 2002 Meeting Minutes from the Los Angeles Regional Water Quality Control Board on February 19 ...
Los Angeles Regional Water Quality Control Board
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Designated centres for older people
, 2009 Swords Nursing Home was first inspected by the Social Services Inspectorate of the Health Information and Quality Authority on 30 July 2009. Inspectors found that the centre failed to comply with the Health Act 2007 (Care and Welfare of Residents in ...
Health Information and Quality Authority (HIQA), Social Service Inspectorate (SSI)
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