Results 111 to 120 of about 1,742,858 (300)

Вплив системи неперервного контролю якості полівінілхлориду на зменшення невизначеності стану технологічного процесу полімеризації [PDF]

open access: yes, 2007
Предложен новый высокоэффективный метод непрерывного контроля комплексного показателя качества суспензионного поливинлхлорида -К в реакторе полимеризации.
Лещій, Р. М.
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Knowing what you know in brain segmentation using Bayesian deep neural networks

open access: yes, 2019
In this paper, we describe a Bayesian deep neural network (DNN) for predicting FreeSurfer segmentations of structural MRI volumes, in minutes rather than hours.
Bandettini, Peter   +9 more
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

PROSPECTS OF CREATION OF QUALITY MANAGEMENT SYSTEM IN SERVICE OF THE EMERGENCY MEDICAL SERVICE

open access: yesНеотложная медицинская помощь, 2016
. Modern approaches to creation of the quality system of medical care, and also relevance and features of its formation in service of an emergency medical service are covered in article.
I. M. Barsukova
doaj  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Water Quality Prediction Method Based on Reinforcement Learning Graph Neural Network

open access: yesIEEE Access
The importance of water quality prediction for management and pollution control has gained significant recognition in recent years. However, existing methods face two main challenges: the interaction between water quality variables and the environment is
Mingming Yan, Zhe Wang
doaj   +1 more source

Manajemen Mutu Terpadu (Tqm) Pada Lembaga Pendidikan Islam [PDF]

open access: yes, 2015
Total Quality Management (TQM) or Total Quality Management in the field of education aimed at improving the quality, competitiveness for outputs (graduates) with an indicator of the competence of both intellectual and skill and intelligent mind ...
KHADIJAH, I. (IFAH)
core  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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