Results 121 to 130 of about 3,714,471 (406)

Complement analysis 2016: Clinical indications, laboratory diagnostics and quality control

open access: yesImmunobiology, 2016
In recent years, complement analysis of body fluids and biopsies, going far beyond C3 and C4, has significantly enhanced our understanding of the disease process. Such expanded complement analysis allows for a more precise differential diagnosis and for critical monitoring of complement-targeted therapy.
Zoltán Prohászka   +3 more
openaire   +3 more sources

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Measuring Food Safety Control in U.S. Hog Farms Using a Composite Indicator [PDF]

open access: yes
Consumer demand for reliable food product quality and safety is growing. This trend, together with increased public regulation and attention to the legal liability of food processors and retailers creates derived demand for food safety assurance in farm ...
Dong, Fengxia, Jensen, Helen H.
core   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Construction of a logical-probabilistic model of casting quality formation for managing technological operations in foundry production [PDF]

open access: yes
The object of the study is the quality of castings manufactured in disposable sand molds. The problem associated with the limitations of existing studies focusing only on individual components in assessing the quality of castings was solved. This imposes
Demin, Dmitriy, Frolova, Liliia
core   +2 more sources

A genome-wide study of Hardy–Weinberg equilibrium with next generation sequence data [PDF]

open access: yes, 2017
Statistical tests for Hardy–Weinberg equilibrium have been an important tool for detecting genotyping errors in the past, and remain important in the quality control of next generation sequence data.
AM Veerappa   +23 more
core   +3 more sources

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Management control for quality in a hospitality business using ARP curves and the multivariate geometric indicator - Control de gestión para la calidad en una empresa hotelera con curvas ARP y el indicador geométrico multivariante

open access: yesSuma de Negocios
Introducción / Objetivo: este estudio tiene como objetivo evaluar la calidad del servicio en una empresa hotelera que opera con tres líneas de atención: preferencial, estándar y básica, bajo condiciones cambiantes.
Tomás José Fontalvo Herrera   +2 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

On the use of cyclostationary indicators in IC engine quality control by cold tests

open access: yesMechanical Systems and Signal Processing, 2015
Abstract This paper addresses the use of first- and second-order cyclostationary (CS1 and CS2) tools to process the vibration signals picked up from internal combustion (IC) engines during cold tests. This type of analysis is needed in order to detect and diagnose irregular operations for quality control purposes.
DELVECCHIO, Simone   +2 more
openaire   +4 more sources

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