Results 71 to 80 of about 6,574,159 (309)

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Learning from the future: towards continuous manufacturing of nanomaterials

AAPS Open
The rise of continuous manufacturing (CM) in the pharmaceutical industry – particularly for the solid oral dosage form—marks a major shift in how drugs are made.
Michael A. VandenBerg, Xiangyi Dong, William C. Smith, Geng Tian, Olen Stephens, Thomas F. O’Connor, Xiaoming Xu   +6 more
doaj   +1 more source

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source

Innovative approach to support therapeutic proteins’ similarity in hydrodynamic size using high-throughput dynamic light scattering and forced degradation

Scientific Reports
Comparative analytical assessment (CAA) between the reference product and the proposed product forms the basis of the biosimilarity demonstration. Though Dynamic Light Scattering (DLS) has been implemented for CAA, its capability beyond signature peak ...
Ashwinkumar Bhirde, Siri Harish, Nicholas Trunfio, Isabella F. de Luna, William Smith, Qiong Fu   +5 more
doaj   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

Simultaneous and absolute quantification of nucleoside triphosphates using liquid chromatography–triple quadrupole tandem mass spectrometry

Genes and Environment, 2018
Background Nucleoside triphosphates participate in fundamental cellular processes as building blocks of DNA and RNA, energy carriers, and cofactors in enzymatic reactions, and their balance is tightly regulated.
Shun Matsuda, Toshihiko Kasahara
doaj   +1 more source

Metabolomics Reveals Distinct Metabolites between Lonicera japonica and Lonicera macranthoides Based on GC-MS

Journal of Chemistry, 2020
Lonicera japonica Thunb. (LJ) and Lonicera macranthoides Hand. -Mazz. (LM) have been widely used in Chinese medicine for thousands of years. Although the morphological characteristics of LJ and LM are quite similar, there are significant distinctions of ...
Rui-ying Liu, Jing Deng, Xiu-Lian Lin, Ya-mei Li, Yan Lin, Bo-hou Xia, Li-mei Lin   +6 more
doaj   +1 more source

Forage Quality Evaluation

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Agriculture, 1970
The challenge for the research in crop and animal husbandry is how to determine the quality of a speci¬fied crop as a forage for ruminants by the chemical analysis of only a small amount of sample". Since more than hundred years scientists try to give an answer to that question.
Lucien CARLIER, Chris VAN WAES, Ioan ROTAR, Mariana VLAHOVA, Roxana VIDICAN   +4 more
openaire   +2 more sources

Evaluating hospital performance based on excess cause-specific incidence [PDF]

, 2015
Formal evaluation of hospital performance in specific types of care is becoming an indispensable tool for quality assurance in the health care system.
Eriksson, Marie, Goetghebeur, Els, Van Rompaye, Bart   +2 more
core   +1 more source