Results 171 to 180 of about 12,119,388 (349)

Image acquisition as novel colonoscopic quality indicator: a single-center retrospective study. [PDF]

Front Oncol, 2023
Zhang K, Bile AM, Feng X, Xu Y, Li Y, She Q, Li G, Wu J, Xiao W, Ding Y, Deng B.   +10 more
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Quality indicator framework for primary care of patients with dementia. [PDF]

Can Fam Physician, 2022
Sourial N, Godard-Sebillotte C, Bronskill SE, Hacker G, Vedel I.   +4 more
europepmc   +1 more source

Care Consistency With Documented Care Preferences: Methodologic Considerations for Implementing the "Measuring What Matters" Quality Indicator.

Journal of Pain and Symptom Management, 2016
K. Unroe, S. Hickman, A. Torke
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Political Ideology and Economic Freedom. [PDF]

This paper examines the association between political ideology and the size of government and quality of the legal system and regulations. A cross-country indicator of government and citizen ideology is presented.
Bjørnskov, Christian
core  

Development of a quality indicator set for day hospices in Germany - a multi-stage, quality-assured review of German guidelines and quality indicator sets. [PDF]

BMC Palliat Care
Kaiser U, Vehling-Kaiser U, Hoffmann A, Kaiser F, Rechenmacher M, Kaiser E, Chalupper R, Fiedler M, Kaiser F.   +8 more
europepmc   +1 more source

Element quality indicator: A quality assessment and defect detection method for software requirement specification. [PDF]

Heliyon, 2023
Zhi Q, Gong L, Ren J, Liu M, Zhou Z, Yamamoto S.   +5 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

School Choice and Quality [PDF]

The 1993 Survey of Household Income and Wealth, a representative survey of the Italian population covering 24,000 individuals, reports detailed information on children's attendance of public and private schools and parents' assessments of the quality of ...
Daniele Checchi, Tullio Jappelli
core