Results 271 to 280 of about 12,119,388 (349)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

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Physician wellness: a missing quality indicator.

Lancet, The, 2009
Jean E. Wallace, Jane B. Lemaire, W. Ghali   +2 more
semanticscholar   +5 more sources

ACOVE Quality Indicators

Annals of Internal Medicine, 2001
This table shows all of the quality indicators published in the Annals of Internal Medicine supplement and on the America College of Physicians-American Society of Internal Medicine.
P G, Shekelle, C H, MacLean, S C, Morton, N S, Wenger   +3 more
openaire   +2 more sources

Quality Indicators for EGD

American Journal of Gastroenterology, 2015
Abbreviations: ACG, American College of Gastroenterology; ASGE, American Society for Gastrointestinal Endoscopy; BE, Barrett’s esophagus; ESD, endoscopic submucosal dissection; PPI, proton pump ...
Walter G, Park, Nicholas J, Shaheen, Jonathan, Cohen, Irving M, Pike, Douglas G, Adler, John M, Inadomi, Loren A, Laine, John G, Lieb, Maged K, Rizk, Mandeep S, Sawhney, Sachin, Wani   +10 more
openaire   +3 more sources

Quality indicators for colonoscopy

Gastrointestinal Endoscopy, 2015
Colonoscopy is widely used for the diagnosis and treatment of colonic disorders. Properly performed, colonoscopy is generally safe, accurate, and well tolerated by most patients. Visualization of the mucosa of the entire large intestine and distal terminal ileum is usually possible at colonoscopy. In patients with chronic diarrhea, biopsy specimens can
Douglas K, Rex, Philip S, Schoenfeld, Jonathan, Cohen, Irving M, Pike, Douglas G, Adler, M Brian, Fennerty, John G, Lieb, Walter G, Park, Maged K, Rizk, Mandeep S, Sawhney, Nicholas J, Shaheen, Sachin, Wani, David S, Weinberg   +12 more
openaire   +3 more sources

Quality Indicators for EUS

American Journal of Gastroenterology, 2015
EUS has become integral to the diagnosis and staging of GI and mediastinal mass lesions and conditions. EUS-guided FNA (EUS-FNA) allows the endoscopist to obtain tissue or fluid for cytologic and chemical analysis, adding to the procedure's utility. Furthermore, the recent development of EUS-guided core biopsy techniques enables his-tologic sampling in
Sachin, Wani, Michael B, Wallace, Jonathan, Cohen, Irving M, Pike, Douglas G, Adler, Michael L, Kochman, John G, Lieb, Walter G, Park, Maged K, Rizk, Mandeep S, Sawhney, Nicholas J, Shaheen, Jeffrey L, Tokar   +11 more
openaire   +3 more sources