Results 221 to 230 of about 20,259,607 (299)

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Quality improvement package for severe tuberculosis triage in Tamil Nadu, India. [PDF]

Public Health Action
Jeyakumar A, Kalaiselvi S, Nair D, Vijayaprabha R, Gayathri K, Kabir D, Melfha JM, Bhatnagar T, Srinivasan R, Balusamy M, Shanmugasundaram S, Catherine A, Nithya N, Venkateshwar R, Frederick A, Shewade HD.   +15 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Comparison between model global AWaRe-based quality indicators and quality indicators developed to assess the appropriateness of antibiotic prescribing in primary healthcare in South Africa. [PDF]

Front Public Health
Chigome AK, Cook A, Heath A, Djukic F, Johnson Y, Essack SY, Brink A, Mendelson M, Campbell SM, Godman B, Meyer JC.   +10 more
europepmc   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Stillbirth and newborn data quality and use and related input and process factors: findings of the IMPULSE study in Ethiopia. [PDF]

J Glob Health
Fisseha D, Abathun F, Cora LG, Worku B, Belgu B, Girmay AM, Chimuna T, Solomon M, Abebe H, Mariani I, Ayele M, Rornald MK, Minja J, Mouhamadou O, Tognon F, Lawn JE, Putoto G, Shamba D, Waiswa P, Awell T, Lazzerini M.   +20 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Uncovering hidden patterns: How good governance and health outcomes are shaped by the public healthcare funding? [PDF]

Front Public Health
Țăran AM, Diaconu M, Vasiu A, Pirtea MG.   +3 more
europepmc   +1 more source