Results 151 to 160 of about 2,480,610 (358)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

DEVELOPMENT AND STANDARDIZATION OF GRANULES IN HARD GELATIN CAPSULES BASED ON THE COMPOSITION OF DRY EXTRACTS OF BIDENS TRIPARTITA, SOLIDAGO CANADENSIS L. AND AGRIMONIA EUPATORIA HERBS

open access: yesРазработка и регистрация лекарственных средств, 2019
The aim of the study is the development and standardization of granules in hard gelatin capsules based on the composition of dry extracts of Bidens tripartita L., Solidago canadensis L. and Agrimonia eupatoria L.
E. K. Novikova   +3 more
doaj  

QUALITY OF PUBLIC TRANSPORTATION SERVICES IN URBAN AREA OF ORADEA [PDF]

open access: yes
Intensification of public transport in urban areas due to increased mobility at regional and national levels, discrepancies among urban areas with same population and lack of statistical data related to performance and quality of public transport ...
Silaghi Simona
core  

Quality Indicators for Emergency Medical Services: The Paramedics' Perspective [PDF]

open access: bronze, 1994
Miles D. Greenberg   +6 more
openalex   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Progress on Drinking Water, Sanitation and Hygiene: 2017 Update and SDG Baselines [PDF]

open access: yes, 2017
The JMP 2017 update report presents indicators and baseline estimates for the drinking water, sanitation and hygiene targets within the Sustainable Development Goals (SDGs).

core  

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

A Latent Variable Model of Quality Determination [PDF]

open access: yes
Despite substantial interest in the determination of quality, there has been little empirical work in the area. The problem, of course, is the general lack of data on quality.
Paul J. Gertler
core  

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