Results 171 to 180 of about 8,832,930 (308)

Welcome to the jungle: collection and evaluation of quality indicators with the QUALICATOR instrument. [PDF]

BMJ Qual Saf
Backes J, Vogel J, Geissler A, Havranek MM, Schladerer SP, Ehlig D, Swiss Quality Monitoring Research Group.   +6 more
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Governance matters IV : governance indicators for 1996-2004 [PDF]

The authors present the latest update of their aggregate governance indicators, together with new analysis of several issues related to the use of these measures. The governance indicators measure the following six dimensions of governance: (1) voice and
Kraay, Aart, Mastruzzi, Massimo, Kaufmann, Daniel   +2 more
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Adherence of Greek gastroenterologists to established quality indicators in gastrointestinal endoscopy. [PDF]

Ann Gastroenterol
Axiaris G, Ioannou A, Dimopoulou K, Papadakos SP, Baxevanis P, Papatheodoridi M, Tsamakidis X, Tziatzios G, Papanikolaou IS, Triantafyllou K, Michopoulos S, Panagiotopoulou K, Paraskeva KD.   +12 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Consumer-reported quality indicators for publicly funded home- and community-based services: development and validation. [PDF]

Gerontologist
Shippee TP, Wolf JM, Parikh RR, Langworthy B, Duan Y, Giordano S, Jutkowitz E.   +6 more
europepmc   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Quality indicators for transcatheter aortic valve implantation in Ontario, Canada: a population-based study. [PDF]

BMJ Open
Aktaa S, Haldenby O, Qiu F, Ko DT, Fremes S, Sud M, Lauck SB, Mamas MA, Blackman DJ, Webb JG, Wijeysundera HC.   +10 more
europepmc   +1 more source