Results 151 to 160 of about 8,832,930 (308)

Evolução da assistência materno-infantil na cidade de São Paulo (1984-1996)

open access: yesRevista de Saúde Pública
OBJETIVO: Descrever a evolução da assistência materno-infantil, com base nas informações extraídas de dois inquéritos domiciliares realizados nos anos de 1984/85 e de 1995/96, na cidade de São Paulo, SP.
Carlos Augusto Monteiro   +2 more
doaj  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

The Graduate Employability Indicators: capturing broader stakeholder perspectives on the achievement and importance of employability attributes.

open access: yes, 2010
With an increasing focus on academic standards, quality and graduate employability outcomes, Australian Higher Education institutions have a greater need to develop and utilise feedback mechanisms to assess and improve graduate employability outcomes ...
Hunt, L.   +6 more
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Female Representation and Quality Indicators in Anesthesiology and Critical Care Podcasts. [PDF]

open access: yesActa Anaesthesiol Scand
Steinsdóttir P   +8 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Quality assessment of high density housing settlements: multi-criteria assessment system and indicators.

open access: yes, 2012
The primary goal of each project is to ensure "the quality of the building work". The quality can be distinguished and classified as: Housing quality; Environmental quality and Technological quality.
PIAIA, Emanuele
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The Quality of Ideas: Measuring Innovation with Multiple Indicators [PDF]

open access: yes
We model early expectations about the value and technological importance ('quality') of a patented innovation as a latent variable common to a set of four indicators: the number of patent claims, forward citations, backward citations and family size. The
Mark Schankerman, Jean O. Lanjouw
core  

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