Results 151 to 160 of about 8,449,104 (300)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Evolução da assistência materno-infantil na cidade de São Paulo (1984-1996)

open access: yesRevista de Saúde Pública
OBJETIVO: Descrever a evolução da assistência materno-infantil, com base nas informações extraídas de dois inquéritos domiciliares realizados nos anos de 1984/85 e de 1995/96, na cidade de São Paulo, SP.
Carlos Augusto Monteiro   +2 more
doaj  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Divergent responses of forage quality indicators to environmental drivers in Eastern Mongolia. [PDF]

open access: yesFront Plant Sci
Jäschke Y   +9 more
europepmc   +1 more source

Why social policy needs subjective indicators [PDF]

open access: yes
There are many qualms about subjective indicators, and some people believe that social policy should better not use them. This paper consists of a review of these objections.
Veenhoven, Ruut
core  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Quality indicators for the management of clinical simulation centers and laboratories: a scoping review. [PDF]

open access: yesRev Lat Am Enfermagem
Santos ISN   +5 more
europepmc   +1 more source

Developing quality indicators for community services: The case of district nursing. Report for NHS Bristol

open access: yes, 2009
Background: Quality indicators exist for the acute and primary care sectors in the National Health Service (NHS), but until recently little attention has been given to measuring the quality of community services.
Davies, P   +3 more
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

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