Results 251 to 260 of about 2,586,340 (358)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Computer-Interpretable Quality Indicators for Intensive Care Medicine: Development and Validation Study.

J Med Internet Res
von Dincklage F, Bublitz VK, Kumpf O, Jurth C, Riessen R, Deja M, Schewe CM, Schädler D, Fuchs C, Gibb S, Scheer C, Schewe JC, Nowak H, Balzer F, Adamzik M, DIVI Information Technology Section, DIVI Quality and Economy Section, Marx G, Lichtner G.   +18 more
europepmc   +1 more source

Improvement of Cancer Care-Analysis of ESGO Quality Indicators for the Surgical Treatment of Endometrial Cancer in Slovenian and Croatian Gynaecologic Oncology Departments. [PDF]

Medicina (Kaunas)
Pakiž M, Klarić M, Dovnik A, Primorac GS, Knez J, Despot Đ, Al Mahdawi L, Pranjic M, Brumec A, Turković T, Cokan A.   +10 more
europepmc   +1 more source

Conformity analysis of sentinel indicators of the water quality of Campina Grande-PB.

, 2013
Polyana de Brito. JANUÁRIO
openalex   +1 more source

Soundscape quality indicators for city parks, the Antwerp case study [PDF]

, 2014
Boes, Michiel, Botteldooren, Dick, De Coensel, Bert, Filipan, Karlo, Oldoni, Damiano   +4 more
core  

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

The Development of Quality Indicators to Assess Family Wellbeing Outcomes Following Engagement with Children's Mental Health Services in Ontario, Canada. [PDF]

Eur J Investig Health Psychol Educ
Stewart SL, Brock BD, Withers A, Guerville RM, Morris JN, Poss JW.   +5 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Quality indicators and turnaround time for blood culture in pediatric patients: 1 year of monitoring in 19 Chinese hospitals. [PDF]

BMC Pediatr
Wu H, Liu W, Peng Y, Qu L, Lin L, Mo B, Cao X, Zhou H, Chen D.   +8 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source