Results 51 to 60 of about 19,791,126 (405)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Evolution and future of total quality management: management control and organisational learning

open access: yesTotal Quality Management and Business Excellence, 2019
The competitive position achieved by the Japanese and Western industries during the 1970s to mid-1990s, and 1980s to mid-1990s, respectively, derived from understanding, implementing, and developing Total Quality Management (TQM) as a comprehensive ...
J. Dahlgaard   +3 more
semanticscholar   +1 more source

ACADEMIC ENTREPRENEURSHIP AND THE EU FUNDS IN POLAND 2014-2020 [PDF]

open access: yesProceedings on Engineering Sciences, 2019
The objective of this paper is to present how the requirements of the EU funds in Poland 2014-2020 force or foster academics to establish and run their own businesses, and/or cooperate with industry.
Anna Prusak   +2 more
doaj   +1 more source

Simulation-Based Analytics for Fabrication Quality-Associated Decision Support [PDF]

open access: yes, 2019
Automated, data-driven quality management systems, which facilitate the transformation of data into useable information, are desired to enhance decision-making processes. Integration of accurate, reliable, and straightforward approaches that measure uncertainty of inspection processes are instrumental for the successful implementation of automated ...
arxiv   +1 more source

Analyzing Dataset Annotation Quality Management in the Wild [PDF]

open access: yesarXiv, 2023
Data quality is crucial for training accurate, unbiased, and trustworthy machine learning models as well as for their correct evaluation. Recent works, however, have shown that even popular datasets used to train and evaluate state-of-the-art models contain a non-negligible amount of erroneous annotations, biases, or artifacts.
arxiv  

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Quality Management of Biorepositories [PDF]

open access: yesBiopreservation and Biobanking, 2015
Biomedical investigators require high quality human tissue to support their research; thus, an important aspect of the provision of tissues by biorepositories is the assurance of high quality and consistency of processing specimens. This is best accomplished by a quality management system (QMS).
Elaine W. Gunter   +3 more
openaire   +3 more sources

Consumers’ Knowledge and Decisions about Choosing Organic Sunscreen Products

open access: yesZeszyty Naukowe Uniwersytetu Ekonomicznego w Krakowie
Objective: The aim of the survey was to assess respondents’ knowledge about organic sunscreen products and to learn about differences in self-assessed levels of knowledge between those who choose and do not choose organic sunscreen products.
Monika Engler-Jastrzębska   +1 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

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