Results 71 to 80 of about 2,567,881 (316)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Integrated Management Systems-Quality, Environment and Safety
, 2002 The implementation of management systems such as the qualrty, environmental and occupational health and safety management systems to the national and/or intemational standards ISO 9000, ISO 14000 and AS/NZS 4801 has been well researched and studied in ...
Akpolat, H, Xu, J
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Tenmile Lakes watershed water quality management plan (WQMP)
, 2007 prepared by Oregon Department of Environmental Quality ; submissions by Oregon Department of Forestry, Oregon Department of Agriculture, Oregon Department of Transportation, Tenmile Lakes Basin Partnership.Title from PDF cover (viewed on March 21, 2023 ...
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AntibioticsBackground/objectives: Antibiotic-resistant Staphylococcus aureus poses a significant risk to food safety and public health, particularly through the consumption of contaminated seafood.
Anita Kukułowicz +2 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
QUALITY MATTERS: ANALYSING THE IMPACT OF COOKING TECHNIQUES ON SELECTED PROPERTIES OF SALMONIDS
Scientific Journal of Gdynia Maritime UniversityThis paper explores the three cooking methods (frying, grilling, and steaming) related to fish most commonly utilized by consumers, with a focus on their implications for both food quality and safety.
Anita Kukułowicz, Arkadiusz Wojtania
doaj +3 more sources
Algorithm for operational planning of transportation by machine shipments in long-distance traffic [PDF]
E3S Web of ConferencesEfficient operational planning of transportation is crucial in longdistance traffic, where the coordination of shipments plays a pivotal role in optimizing logistics operations.
Novokshonov Nikita +4 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
The challenge of integrating innovation and quality management practice
, 2016 Following in the footsteps of ‘New Public Management’, where quality management and quality control have become widely implemented concepts among public authorities, there is now a subsequent government demand to also be innovative.
Lilja, Johan, +2 more
core +1 more source