Results 91 to 100 of about 2,567,881 (316)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Workplace stress and health - the connection to quality management
, 2022 Stress and bullying create severe pressure on workplace health. Although the connection between quality management and health is beginning to be well established, the association to workplace stress and workplace bullying has not been previously studied.
Lagrosen, Yvonne +3 more
core +1 more source
Hazards Related to the Safety of Rice Available on the Common Market of the European Union
ResourcesDespite relatively low per capita rice consumption in the European Union (EU), averaging approximately 9 kg annually between 2010 and 2023, imports from Asian countries have shown a sustained upward trend since 2013.
Marcin Pigłowski, Maria Śmiechowska
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
A conceptual framework for hospital quality management
, 2003 Most current conceptual frameworks used for hospital quality management exhibit shortcomings, terminology barriers or too much complexity. We propose a rigorous and simple model specific to hospitals, based on four entities (patients, activities ...
Eggli, Yves, Halfon, Patricia
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Managing Performance: Quality and Project Management - Raw Materials
, 2011 The raw materials which make up the Managing Performance: Quality and Project Management Learning Activity which provides an insight into project and quality management.
EVOLUTION +4 more
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source