Results 101 to 110 of about 16,937,020 (309)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Quality Management System

open access: yesJournal of Clinical and Biomedical Sciences, 2021
Subhashish Das
doaj   +1 more source

Quality management issues

open access: yesSeminars in Oncology Nursing, 1993
T HE CARE and treatment of the cancer patient is a highly complex activity. Multiple professional staff and family members are involved. Physicians and staff from several organizations may contribute to the overall care plan for the patient. Different professionals each have their role.
openaire   +2 more sources

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Hazards Related to the Safety of Rice Available on the Common Market of the European Union

open access: yesResources
Despite relatively low per capita rice consumption in the European Union (EU), averaging approximately 9 kg annually between 2010 and 2023, imports from Asian countries have shown a sustained upward trend since 2013.
Marcin Pigłowski, Maria Śmiechowska
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Developing a TQM quality management method model [PDF]

open access: yes
From an extensive review of total quality management literature, the external and internal environment affecting an organization's quality performance and the eleven primary elements of TQM are identified. Based on the primary TQM elements, a TQM quality
Zhang, Zhihai
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Development and psychometric validation of the hospital Security Personnel Narrative Competency Scale (HSPNCS)

open access: yesBMC Health Services Research
Background Hospital security personnel frequently interact with patients and families in emotionally complex and potentially conflict-prone situations. However, no specific instrument is available to assess narrative competency in this healthcare support
Binru Fang   +7 more
doaj   +1 more source

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