Results 111 to 120 of about 16,137,384 (304)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Public review draft, Portland Harbor sediment management plan
, 1999 Main report -- appendix A. Letter from EPA to DEQ dated March 22, 1999 -- appendix B. DEQ funding agreement, agreement between the Portland Harbor Group and the Oregon Department of Environmental Quality for preparation of the Portland Harbor Sediment ...
core
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2009 Within the contemporary economic conditions, enterprises might achieve a competitive advantage if only they sell goods and services with high quality and lower prices. Customers, usually, prefer quality goods with acceptable prices, while such goods create reputation with the particular brand.
Vitanova, Gordana, Spaseska, Tatjana
openaire +1 more source
Developing a TQM quality management method model [PDF]
From an extensive review of total quality management literature, the external and internal environment affecting an organization's quality performance and the eleven primary elements of TQM are identified. Based on the primary TQM elements, a TQM quality
Zhang, Zhihai
core
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
FOOD SAFETY SYSTEMS’ FUNCTIONING IN POLISH NETWORKS OF GROCERY STORES [PDF]
Management Systems in Production Engineering, 2013 This article shows the way how the food safety systems are functioning in Polish networks of grocery stores. The study was conducted in the fourth quarter of 2012 in the south‐eastern Poland.
Paweł NOWICKI +2 more
doaj
Increasing the value of quality management systems
, 2019 Over one million organisations have a Quality Management System (QMS) certified to the ISO9000 standard; however, the system requires a lot of resources and its value has been questioned. The purpose of this paper is to investigate how different types of
Elg, Mattias, +3 more
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Environmental Sciences EuropeBackground Per- and polyfluoroalkyl substances (PFAS) are emerging organic pollutants widely detected in environmental systems, posing risks to human health and the ecosystem.
Meiqi Liu +10 more
doaj +1 more source