Results 101 to 110 of about 9,502,909 (338)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Analysis of the Theories for Assessment of the Quality Management Product Efficiency

Журнал інженерних наук, 2018
In the article the advantages of introduction and reasons of low efficiency of the quality management system at the machine-building enterprises are determined. The methods and tools of the quality management system are considered. The conducted analysis
Zaloga V., Yashyna T., Dynnyk O.
doaj   +1 more source

Montefiore Medical Center: Integrated Care Delivery for Vulnerable Populations [PDF]

, 2010
Describes a system of hospitals and community- and school-based clinics tailored to low-income patients through systemwide strategies, high-quality specialty and hospital care, and integrated care delivery via care management and information ...
Deborah Chase
core  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Preparation process for implantation of the quality management system: study of the difficulties from viewpoint of quality management department staff

GEPROS: Gestão da Produção, Operações e Sistemas, 2016
Based on the need for continuous improvement by companies to differentiate themselves against competitors and provide reliability to customers, quality management systems prove to be a valuable tool.
Jaiane Aparecida Pereira, Denise Alves Graciano, Reginaldo Aparecido Verri   +2 more
doaj   +1 more source

Institutions and Water -- the Vital Connections [PDF]

This Policy Notes looks into the current two-tiered system of water governance in the Philippines. It argues that despite the presence of certain national-local interfaces among the institutions involved in water governance, the multiplicity of ...
Elazegui, Dulce D.
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Integration management system – new of requirements of ISO 9001:2015 and ISO 14001:2015 standards

Production Engineering Archives, 2016
Organizations are becoming more aware of the importance of integrated management systems (IMS). Interest in this subject indicates that IMS are seen as "management systems of the future“.
Renata Nováková, Katarína Čekanová, Alena Pauliková   +2 more
doaj  

QUALITY MANAGEMENT PRINCIPLES – AN APPROACH IN HEALTHCARE INSTITUTIONS [PDF]

The problems of quality management systems development don´t seem to be interesting for healthcare institutions (HCI) at a glance. But a lot of managers and employees of HCI (including physicians) have already understood that their organizations also ...
Kristina Zgodavova, Sofia Elena Colesca
core  

Implementation of the quality management system improves postoperative pain treatment: a prospective pre-/post-interventional questionnaire study

British Journal of Anaesthesia, 2012
Background An organizational approach is proposed as an immediate solution for improving postoperative pain (POP) management. The aim was to evaluate the clinical effectiveness of a quality management system (QMS), based on procedure-specific, multimodal
T. Usichenko, I. Röttenbacher, T. Kohlmann, Andreas Jülich, Joern Lange, Alexander Mustea, G. Engel, Michael Wendt   +7 more
semanticscholar   +1 more source