Results 51 to 60 of about 8,962,902 (386)
Implementation Science Communications, 2020 An amendment to this paper has been published and can be accessed via the original article.
Edward J. Miech +8 more
doaj +1 more source
Regional co-variability of spatial and temporal soil moisture–precipitation coupling in North Africa: an observational perspective [PDF]
Hydrology and Earth System Sciences, 2018 The magnitude and sign of soil moisture–precipitation coupling (SMPC) is investigated using a probability-based approach and 10 years of daily microwave satellite data across North Africa at a 1° horizontal scale. Specifically, the co-existence and co-
I. Y. Petrova +4 more
doaj +1 more source
Developing an Active Canopy Sensor-Based Integrated Precision Rice Management System for Improving Grain Yield and Quality, Nitrogen Use Efficiency, and Lodging Resistance [PDF]
, 2022 Junjun Lu +6 more
openalex +1 more source
Integrating automated support for a software management cycle into the TAME system [PDF]
, 1989 Software managers are interested in the quantitative management of software quality, cost and progress. An integrated software management methodology, which can be applied throughout the software life cycle for any number purposes, is required. The TAME (
Basili, Victor R., Sunazuka, Toshihiko
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
KNOWLEDGE MANAGEMENT TECHNOLOGIES IN VIEW OF IMPLEMENTATION OF QUALITY MANAGEMENT
Вісник Київського національного університету імені Тараса Шевченка. Серія Економіка, 2015 The paper reveals actual problems of development and implementation of international quality standards. Authors proposed KM-oriented model of organizational learning both in view of implementation of total quality management concept and realization of ...
L. Anisimova, V. Pryimak
doaj +1 more source
Early warning signals of tipping points in periodically forced systems [PDF]
Earth System Dynamics, 2016 The prospect of finding generic early warning signals of an approaching tipping point in a complex system has generated much interest recently. Existing methods are predicated on a separation of timescales between the system studied and its forcing ...
M. S. Williamson +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
International Journal of Integrated Care, 2019 Introduction: Transitions in care between and within healthcare sectors are a major focus across health jurisdictions. It is a time of vulnerability for both patients and their families.
Sara J.T. Guilcher +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source