Results 121 to 130 of about 4,092,098 (300)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Systemic treatment of quality management quality management system

open access: yes, 2014
Managementul calităţii totale TQM formează un set de practici manageriale în cadrul organizaţiei, orientate spre îndeplinirea în mod constant a cerinţelor clientului sau chiar spre depăşirea acestora.TQM este o abordare pe care organizaţiile o folosesc pentru a îmbunătăţi procesele interne şi a asigura satisfacţia clienţilor.
openaire   +1 more source

Deteriorating Cost Efficiency in Commercial Banks Signals an Increasing Risk of Failure [PDF]

open access: yes
While it is generally consented that management quality is often the key determinant of banks' success in a risky world, somewhat paradoxically early warning systems are mainly built on financial ratios driving management quality assessment to the ...
Anca Podpiera, Jiri Podpiera
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Strategies to improve quality and safety and reduce cost of production in organic and low-input crop production systems. QLIF subproject 3: Crop production methods [PDF]

open access: yes, 2009
Organic crop production seeks to produce high quality foods while reducing the inputs in order to promote environmental quality and conserve resources. This necessitates optimal production systems in terms of soil fertility and plant health.
Tamm, L.
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Certification of quality management systems under ISO 9000 versus business bottom line: empirical evidence [PDF]

open access: yes, 2009
Esta investigación, tiene como objetivo principal la posible correlación entre la calidad y los beneficios que proporciona, tanto humanos, económicos y tecnológicos, materializados en un incremento de los resultados, lo que permitirá algunas empresas ...
Cossío Silva, Francisco José (Coordinador)   +2 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

quality management system

open access: yes
Citation: 'quality management system' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.08110 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
  +6 more sources

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